Polineuropatie associate a discrasie linfoplasmacellulari: caratteristiche cliniche e strumentali di una casistica di 38 pazienti.

Translated title of the contribution: Polyneuropathies associated with lymphoplasmacytic dyscrasias: the clinical and instrumental characteristics of a 38-patient case load

S. Rupoli, F. Logullo, P. di Bella, M. F. Brianzoni, A. Salvi, S. D'Amico, A. Olivieri, P. Leoni

Research output: Contribution to journalArticle

Abstract

A varying percentage from 40 to 60% of patients having lymphoplasmacytic dyscrasias with a monoclonal component shows a clinical or subclinical polyneuropathy. From a different viewpoint, a monoclonal gammopathy has been detected in 10% of patients effected by chronic idiopathic polyneuropathy. A case study of 38 patients with lymphoplasmacytic dyscrasia subjected to clinical, immunohematological and electrophysiological examination revealed a high prevalence of polyneuropathy (84%), mainly axonal (72%) and often subclinical. The neuropathy was evenly distributed between patients having malignant and benign lymphoplasmacytic dyscrasias. No statistically significant correlation was found between the presence of neuropathy and the main clinical and immunohematological data. This supports the concept that the pathogenesis of polyneuropathy associated with lymphoplasmacytic dyscrasias may be multifactorial. Nor can it be ruled out that the paraprotein may in fact be secondary to the polyneuropathy or sometimes a simple coincidence.

Translated title of the contributionPolyneuropathies associated with lymphoplasmacytic dyscrasias: the clinical and instrumental characteristics of a 38-patient case load
Original languageItalian
Pages (from-to)541-545
Number of pages5
JournalRecenti Progressi in Medicina
Volume83
Issue number10
Publication statusPublished - Oct 1992

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Polyneuropathies associated with lymphoplasmacytic dyscrasias: the clinical and instrumental characteristics of a 38-patient case load'. Together they form a unique fingerprint.

  • Cite this

    Rupoli, S., Logullo, F., di Bella, P., Brianzoni, M. F., Salvi, A., D'Amico, S., Olivieri, A., & Leoni, P. (1992). Polineuropatie associate a discrasie linfoplasmacellulari: caratteristiche cliniche e strumentali di una casistica di 38 pazienti. Recenti Progressi in Medicina, 83(10), 541-545.