Polypharmacy and sarcopenia in hospitalized older patients: results of the GLISTEN study

For The Glisten Group Investigators

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Abstract

Background: Recently the Berlin Aging Study II (BASE-II) showed that polypharmacy is associated with clinically relevant sarcopenia among community-dwelling older persons. Here we report findings from the GLISTEN study about the association of polypharmacy with sarcopenia among older medical in-patients. Methods: The GLISTEN study investigated prevalence and clinical correlates of sarcopenia in older patients admitted to geriatric and internal medicine acute care wards of 12 Italian hospitals. Results: In this sample of older medical in-patients with high prevalence of sarcopenia (34.7%) and polypharmacy (70.2%) we did not observe a significant association of polypharmacy with sarcopenia. Conclusions: Present findings demonstrate that the association of polypharmacy with sarcopenia, observed in the BASE-II study, is not evident in the GLISTEN sample, being our patients significantly older, more multi-morbid, with high prevalence of sarcopenia and polypharmacy, suggesting that this association might vary according to the heterogeneous health, functional, and nutritional characteristics of older people.

Original languageEnglish
Pages (from-to)557-559
Number of pages3
JournalAging clinical and experimental research
Volume31
Issue number4
DOIs
Publication statusPublished - Apr 1 2019

Keywords

  • In-patients
  • Polypharmacy
  • Sarcopenia
  • Skeletal muscle

ASJC Scopus subject areas

  • Ageing
  • Geriatrics and Gerontology

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