Polyphenolic antioxidant (-)-epigallocatechin-3-gallate from green tea as a candidate anti-HIV agent

Gianfranco Fassina, Anna Buffa, Roberto Benelli, Oliviero E. Varnier, Douglas M. Noonan, Adriana Albini

Research output: Contribution to journalArticlepeer-review

Abstract

Epigallocatechin-3-gallate (EGCG), one of the components of green tea, has been suggested to have antiviral activity. To determine the effects of EGCG on HIV infection, peripheral blood lymphocytes were incubated with either LAI/IIIB or Bal HIV strains and increasing concentrations of EGCG. EGCG strongly inhibited the replication of both virus strains as determined by reverse transcriptase and p24 assays on the cell supernatants.

Original languageEnglish
Pages (from-to)939-941
Number of pages3
JournalAIDS (London, England)
Volume16
Issue number6
DOIs
Publication statusPublished - Apr 12 2002

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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