Polysaccharides are the main sources of biomolecules for the use as biomaterials in pharmacology and cosmetology: cellulose, alginate, pollulanes and chitin derivatives belong to this class of substances. The aim of the present study was to evaluate the properties of N-carboxybutil-chitosan as biomaterials to aid skin repair processes. Morphological evaluations showed the ability of N-carboxybutil-chitosan to affect favourably collagen and extracellular matrix deposition, and confirmed the degradability of this molecule. Tissue repaired in presence of chitosan showed better histoarchiectural features with mature cell elements and orderly arrangement of collagen fibres than control areas.
|Number of pages||8|
|Journal||Journal of Applied Cosmetology|
|Publication status||Published - Jul 1999|
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