Abstract
Polysaccharides are the main sources of biomolecules for the use as biomaterials in pharmacology and cosmetology: cellulose, alginate, pollulanes and chitin derivatives belong to this class of substances. The aim of the present study was to evaluate the properties of N-carboxybutil-chitosan as biomaterials to aid skin repair processes. Morphological evaluations showed the ability of N-carboxybutil-chitosan to affect favourably collagen and extracellular matrix deposition, and confirmed the degradability of this molecule. Tissue repaired in presence of chitosan showed better histoarchiectural features with mature cell elements and orderly arrangement of collagen fibres than control areas.
| Original language | English |
|---|---|
| Pages (from-to) | 94-101 |
| Number of pages | 8 |
| Journal | Journal of Applied Cosmetology |
| Volume | 17 |
| Issue number | 3 |
| Publication status | Published - Jul 1999 |
Keywords
- Health
- N-carboxybutyl-chitosan
- Wound-healing
ASJC Scopus subject areas
- Dermatology