Abstract
The aim of this study was to assess the presence of sleep breathing disorder and periodic leg movements during sleep (PLMS), and to evaluate NREM sleep instability in a group of children with mental retardation (MR) and epilepsy. Eleven subjects with MR and epilepsy (6 males, age range 9-17 years) were recruited for this study. A control group was formed by 11 age-matched normal children. Three children with MR and epilepsy showed an apnea-hypopnea index > 5, two of them had also a PLMS index > 5. Another subject had only a PLMS index > 5. Children with MR showed many sleep architecture differences compared to controls. They also showed higher cyclic alternating pattern (CAP) rate, increased A1 index, long and less numerous CAP sequences than controls. A detailed investigation and treatment of sleep disorders in children affected by MR and epilepsy may have a positive impact on seizure control.
| Original language | English |
|---|---|
| Pages (from-to) | 575-583 |
| Number of pages | 9 |
| Journal | Neurological Sciences |
| Volume | 31 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Oct 2010 |
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Keywords
- Cyclic alternating pattern
- Intellectual disability
- Mental retardation
- Periodic leg movements during sleep
- Sleep architecture
- Sleep breathing disorder
ASJC Scopus subject areas
- Dermatology
- Clinical Neurology
- Psychiatry and Mental health
Cite this
Polysomnographic assessment of sleep disturbances in children with developmental disabilities and seizures. / Miano, Silvia; Bruni, Oliviero; Aricò, Debora; Elia, Maurizio; Ferri, Raffaele.
In: Neurological Sciences, Vol. 31, No. 5, 10.2010, p. 575-583.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Polysomnographic assessment of sleep disturbances in children with developmental disabilities and seizures
AU - Miano, Silvia
AU - Bruni, Oliviero
AU - Aricò, Debora
AU - Elia, Maurizio
AU - Ferri, Raffaele
PY - 2010/10
Y1 - 2010/10
N2 - The aim of this study was to assess the presence of sleep breathing disorder and periodic leg movements during sleep (PLMS), and to evaluate NREM sleep instability in a group of children with mental retardation (MR) and epilepsy. Eleven subjects with MR and epilepsy (6 males, age range 9-17 years) were recruited for this study. A control group was formed by 11 age-matched normal children. Three children with MR and epilepsy showed an apnea-hypopnea index > 5, two of them had also a PLMS index > 5. Another subject had only a PLMS index > 5. Children with MR showed many sleep architecture differences compared to controls. They also showed higher cyclic alternating pattern (CAP) rate, increased A1 index, long and less numerous CAP sequences than controls. A detailed investigation and treatment of sleep disorders in children affected by MR and epilepsy may have a positive impact on seizure control.
AB - The aim of this study was to assess the presence of sleep breathing disorder and periodic leg movements during sleep (PLMS), and to evaluate NREM sleep instability in a group of children with mental retardation (MR) and epilepsy. Eleven subjects with MR and epilepsy (6 males, age range 9-17 years) were recruited for this study. A control group was formed by 11 age-matched normal children. Three children with MR and epilepsy showed an apnea-hypopnea index > 5, two of them had also a PLMS index > 5. Another subject had only a PLMS index > 5. Children with MR showed many sleep architecture differences compared to controls. They also showed higher cyclic alternating pattern (CAP) rate, increased A1 index, long and less numerous CAP sequences than controls. A detailed investigation and treatment of sleep disorders in children affected by MR and epilepsy may have a positive impact on seizure control.
KW - Cyclic alternating pattern
KW - Intellectual disability
KW - Mental retardation
KW - Periodic leg movements during sleep
KW - Sleep architecture
KW - Sleep breathing disorder
UR - http://www.scopus.com/inward/record.url?scp=78049340007&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78049340007&partnerID=8YFLogxK
U2 - 10.1007/s10072-010-0291-8
DO - 10.1007/s10072-010-0291-8
M3 - Article
C2 - 20506030
AN - SCOPUS:78049340007
VL - 31
SP - 575
EP - 583
JO - Neurological Sciences
JF - Neurological Sciences
SN - 1590-1874
IS - 5
ER -