Polysomnographic assessment of sleep disturbances in children with developmental disabilities and seizures

Silvia Miano; Oliviero Bruni; Debora Aricò; Maurizio Elia; Raffaele Ferri

doi:10.1007/s10072-010-0291-8

Polysomnographic assessment of sleep disturbances in children with developmental disabilities and seizures

Silvia Miano, Oliviero Bruni, Debora Aricò, Maurizio Elia, Raffaele Ferri

www.irccs.oasi.en.it

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Abstract

The aim of this study was to assess the presence of sleep breathing disorder and periodic leg movements during sleep (PLMS), and to evaluate NREM sleep instability in a group of children with mental retardation (MR) and epilepsy. Eleven subjects with MR and epilepsy (6 males, age range 9-17 years) were recruited for this study. A control group was formed by 11 age-matched normal children. Three children with MR and epilepsy showed an apnea-hypopnea index > 5, two of them had also a PLMS index > 5. Another subject had only a PLMS index > 5. Children with MR showed many sleep architecture differences compared to controls. They also showed higher cyclic alternating pattern (CAP) rate, increased A1 index, long and less numerous CAP sequences than controls. A detailed investigation and treatment of sleep disorders in children affected by MR and epilepsy may have a positive impact on seizure control.

Original language	English
Pages (from-to)	575-583
Number of pages	9
Journal	Neurological Sciences
Volume	31
Issue number	5
DOIs	https://doi.org/10.1007/s10072-010-0291-8
Publication status	Published - Oct 2010

Keywords

Cyclic alternating pattern
Intellectual disability
Mental retardation
Periodic leg movements during sleep
Sleep architecture
Sleep breathing disorder

ASJC Scopus subject areas

Dermatology
Clinical Neurology
Psychiatry and Mental health

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abstract = "The aim of this study was to assess the presence of sleep breathing disorder and periodic leg movements during sleep (PLMS), and to evaluate NREM sleep instability in a group of children with mental retardation (MR) and epilepsy. Eleven subjects with MR and epilepsy (6 males, age range 9-17 years) were recruited for this study. A control group was formed by 11 age-matched normal children. Three children with MR and epilepsy showed an apnea-hypopnea index > 5, two of them had also a PLMS index > 5. Another subject had only a PLMS index > 5. Children with MR showed many sleep architecture differences compared to controls. They also showed higher cyclic alternating pattern (CAP) rate, increased A1 index, long and less numerous CAP sequences than controls. A detailed investigation and treatment of sleep disorders in children affected by MR and epilepsy may have a positive impact on seizure control.",

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