Polysomnographic assessment of sleep disturbances in children with developmental disabilities and seizures

Silvia Miano, Oliviero Bruni, Debora Aricò, Maurizio Elia, Raffaele Ferri

Research output: Contribution to journalArticle

Abstract

The aim of this study was to assess the presence of sleep breathing disorder and periodic leg movements during sleep (PLMS), and to evaluate NREM sleep instability in a group of children with mental retardation (MR) and epilepsy. Eleven subjects with MR and epilepsy (6 males, age range 9-17 years) were recruited for this study. A control group was formed by 11 age-matched normal children. Three children with MR and epilepsy showed an apnea-hypopnea index > 5, two of them had also a PLMS index > 5. Another subject had only a PLMS index > 5. Children with MR showed many sleep architecture differences compared to controls. They also showed higher cyclic alternating pattern (CAP) rate, increased A1 index, long and less numerous CAP sequences than controls. A detailed investigation and treatment of sleep disorders in children affected by MR and epilepsy may have a positive impact on seizure control.

Original languageEnglish
Pages (from-to)575-583
Number of pages9
JournalNeurological Sciences
Volume31
Issue number5
DOIs
Publication statusPublished - Oct 2010

Fingerprint

Developmental Disabilities
Disabled Children
Intellectual Disability
Sleep
Seizures
Epilepsy
Leg
Post-Traumatic Epilepsy
Apnea
Respiration
Control Groups

Keywords

  • Cyclic alternating pattern
  • Intellectual disability
  • Mental retardation
  • Periodic leg movements during sleep
  • Sleep architecture
  • Sleep breathing disorder

ASJC Scopus subject areas

  • Dermatology
  • Clinical Neurology
  • Psychiatry and Mental health

Cite this

Polysomnographic assessment of sleep disturbances in children with developmental disabilities and seizures. / Miano, Silvia; Bruni, Oliviero; Aricò, Debora; Elia, Maurizio; Ferri, Raffaele.

In: Neurological Sciences, Vol. 31, No. 5, 10.2010, p. 575-583.

Research output: Contribution to journalArticle

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