Politerapia e polifarmacia nell'anziano con scompenso cardiaco cronico

Translated title of the contribution: Polytherapy and polypharmacy in the elderly with chronic heart failure

Nicola Ferrara, Pierfranco Terrosu, Giuseppe Zuccalà, Alberto Corsini

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Population aging is associated with an increasing prevalence of chronic diseases(including chronic heart failure) and comorbidities(the presence of one or more diseases in addition to an index disease, potentially contributing to disability) which, in turn, expands the need for healthcare services. Therefore, the already elevated costs in the National Health Services are expected to rise further over the next decades, along with increasing aging of the population. This epidemiologic trend is responsible for the increasing occurrence of polytherapy(multiple medications prescribed to an individual patient) and polypharmacy(multiple medications not directly prescribed by a physician). Owing to often unpredictable interactions, polytherapy and polypharmacy are associated with higher risk of adverse drug reactions with increased mortality and hospitalizations that contribute to increase direct and indirect National Health Services costs. Physicians, patients and caregivers should be instructed in strategies aimed at reducing adverse drug reactions while maintaining optimal management of conditions that, such as chronic heart failure, are at high risk of death, functional impairment and deteriorated quality of life. Strategies consist of a variety of interventions, such as reducing inappropriate medication prescriptions and number of medications and doses taken, avoiding drugs with greater potential of interactions, and increasing patient adherence.

Original languageItalian
JournalGiornale Italiano di Cardiologia
Volume14
Issue number3 SUPPL1
DOIs
Publication statusPublished - Mar 2013

Fingerprint

Polypharmacy
National Health Programs
Drug-Related Side Effects and Adverse Reactions
Heart Failure
Inappropriate Prescribing
Physicians
Patient Compliance
Health Care Costs
Caregivers
Population
Comorbidity
Hospitalization
Chronic Disease
Quality of Life
Delivery of Health Care
Costs and Cost Analysis
Mortality
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Politerapia e polifarmacia nell'anziano con scompenso cardiaco cronico. / Ferrara, Nicola; Terrosu, Pierfranco; Zuccalà, Giuseppe; Corsini, Alberto.

In: Giornale Italiano di Cardiologia, Vol. 14, No. 3 SUPPL1, 03.2013.

Research output: Contribution to journalArticle

Ferrara, Nicola ; Terrosu, Pierfranco ; Zuccalà, Giuseppe ; Corsini, Alberto. / Politerapia e polifarmacia nell'anziano con scompenso cardiaco cronico. In: Giornale Italiano di Cardiologia. 2013 ; Vol. 14, No. 3 SUPPL1.
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