Ponatinib treatment in chronic myeloid leukemia cell lines targets aurora kinase A/FOXM1 axis

Manuela Mancini, Sara De Santis, Cecilia Monaldi, Luana Bavaro, Margherita Martelli, Gabriele Gugliotta, Fausto Castagnetti, Gianantonio Rosti, Maria Alessandra Santucci, Giovanni Martinelli, Michele Cavo, Simona Soverini

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)201-203
Number of pages3
JournalHematological Oncology
Volume38
Issue number2
DOIs
Publication statusPublished - Apr 2020

Keywords

  • Apoptosis/drug effects
  • Aurora Kinase A/genetics
  • Cell Proliferation/drug effects
  • Drug Resistance, Neoplasm
  • Forkhead Box Protein M1/genetics
  • Gene Expression Regulation, Neoplastic/drug effects
  • Humans
  • Imidazoles/pharmacology
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy
  • Protein Kinase Inhibitors/pharmacology
  • Pyridazines/pharmacology
  • Tumor Cells, Cultured

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