Abstract
Background: The percentages of breast cancer cases in a given population attributable to specific risk factors (i.e., the population-attributable risks) can be calculated; determination of such risks associated with potentially modifiable risks factors, such as diet (e.g., levels of consumption of fruits, vegetables, vitamins, etc.), alcohol consumption, exercise, and body weight, are necessary to focus prevention strategies. Methods: With the use of data from a case-control study conducted in Italy from June 1991 through April 1994 on 2569 breast cancer case subjects and 2588 control subjects, we calculated multivariate odds ratios and population- attributable risks for breast cancer in relation to dietary β-carotene and vitamin E intake, alcohol consumption, physical activity, and, for postmenopausal women, body mass index. Results: Among all subjects, the following attributable risks for the indicated risk factors were observed: 10.7% (95% confidence interval [CI] = 4.4%-17.0%) for high alcohol intake (i.e., >20 g/day), 15.0% (95% CI = 7.4%-22.9%) for low β-carotene intake (i.e.,
| Original language | English |
|---|---|
| Pages (from-to) | 389-394 |
| Number of pages | 6 |
| Journal | Journal of the National Cancer Institute |
| Volume | 90 |
| Issue number | 5 |
| Publication status | Published - Mar 4 1998 |
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ASJC Scopus subject areas
- Cancer Research
- Oncology
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Population attributable risk for breast cancer : Diet, nutrition, and physical exercise. / Mezzetti, Maura; La Vecchia, Carlo; Decarli, Adriano; Boyle, Peter; Talamini, Renato; Franceschi, Silvia.
In: Journal of the National Cancer Institute, Vol. 90, No. 5, 04.03.1998, p. 389-394.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Population attributable risk for breast cancer
T2 - Diet, nutrition, and physical exercise
AU - Mezzetti, Maura
AU - La Vecchia, Carlo
AU - Decarli, Adriano
AU - Boyle, Peter
AU - Talamini, Renato
AU - Franceschi, Silvia
PY - 1998/3/4
Y1 - 1998/3/4
N2 - Background: The percentages of breast cancer cases in a given population attributable to specific risk factors (i.e., the population-attributable risks) can be calculated; determination of such risks associated with potentially modifiable risks factors, such as diet (e.g., levels of consumption of fruits, vegetables, vitamins, etc.), alcohol consumption, exercise, and body weight, are necessary to focus prevention strategies. Methods: With the use of data from a case-control study conducted in Italy from June 1991 through April 1994 on 2569 breast cancer case subjects and 2588 control subjects, we calculated multivariate odds ratios and population- attributable risks for breast cancer in relation to dietary β-carotene and vitamin E intake, alcohol consumption, physical activity, and, for postmenopausal women, body mass index. Results: Among all subjects, the following attributable risks for the indicated risk factors were observed: 10.7% (95% confidence interval [CI] = 4.4%-17.0%) for high alcohol intake (i.e., >20 g/day), 15.0% (95% CI = 7.4%-22.9%) for low β-carotene intake (i.e.,
AB - Background: The percentages of breast cancer cases in a given population attributable to specific risk factors (i.e., the population-attributable risks) can be calculated; determination of such risks associated with potentially modifiable risks factors, such as diet (e.g., levels of consumption of fruits, vegetables, vitamins, etc.), alcohol consumption, exercise, and body weight, are necessary to focus prevention strategies. Methods: With the use of data from a case-control study conducted in Italy from June 1991 through April 1994 on 2569 breast cancer case subjects and 2588 control subjects, we calculated multivariate odds ratios and population- attributable risks for breast cancer in relation to dietary β-carotene and vitamin E intake, alcohol consumption, physical activity, and, for postmenopausal women, body mass index. Results: Among all subjects, the following attributable risks for the indicated risk factors were observed: 10.7% (95% confidence interval [CI] = 4.4%-17.0%) for high alcohol intake (i.e., >20 g/day), 15.0% (95% CI = 7.4%-22.9%) for low β-carotene intake (i.e.,
UR - http://www.scopus.com/inward/record.url?scp=0032481581&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032481581&partnerID=8YFLogxK
M3 - Article
C2 - 9498489
AN - SCOPUS:0032481581
VL - 90
SP - 389
EP - 394
JO - Journal of the National Cancer Institute
JF - Journal of the National Cancer Institute
SN - 0027-8874
IS - 5
ER -