Population-based frequency assessment of HPV-induced lesions in patients with borderline Pap tests in the Emilia-Romagna Region: The PATER study

S. Costa, S. Venturoli, F. S. Mennini, A. Marcellusi, M. Pesaresi, E. Leo, A. Falasca, E. Marra, M. Cricca, D. Santini, M. Zerbini, G. Pelusi

Research output: Contribution to journalArticlepeer-review

Abstract

Background: The PATER study assessed the frequency of high-risk (HR) and low-risk (LR) human papillomavirus (HPV) in HPV-induced lesions in patients with borderline cytology. Methods: This retrospective observational cohort study was designed to evaluate ASCUS patients detected through a local cervical cancer screening programme and referred to the Department of Gynaecology and Obstetrics at the S. Orsola-Malpighi University Hospital in Bologna, in the period between January 2000 and December 2007. Results: In 1047 patients aged 38.4±Â±9.6 years (range 23"65 years), 34.8% (n=364) was positive for HR- or LR-HPV DNA. The mean age of women with HPV infection was significantly lower compared with the negative group (36. 8±Â±9.4 versus 39.3±Â±9.6 years; p

Original languageEnglish
Pages (from-to)569-578
Number of pages10
JournalCurrent Medical Research and Opinion
Volume27
Issue number3
DOIs
Publication statusPublished - Mar 2011

Keywords

  • Borderline cytology
  • Cervical cancer screening
  • CIN lesions
  • HR-HPV
  • LR-HPV

ASJC Scopus subject areas

  • Medicine(all)

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