Abstract
One of the topics of the biomedical research is to design and develop new drug delivery systems able to perform time-controlled release of medicals with target specificity. Porous silicon, characterized by macropores of 2 μm average diameter, with a 200 nm thick nanoporous coverage, was produced and its potential applications as drug-carrier were investigated. Doxorubicin loaded porous silicon bits exhibited a time-depending drug delivery profile that is in trend with the cytotoxicity of adenocarcinoma cancer cells exposed to bits.
Original language | English |
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Pages (from-to) | 1598-1601 |
Number of pages | 4 |
Journal | Microelectronic Engineering |
Volume | 83 |
Issue number | 4-9 SPEC. ISS. |
DOIs | |
Publication status | Published - Apr 2006 |
Keywords
- Controlled Drug Delivery
- Doxorubicin
- Porous Silicon
- Post-surgical Chemotherapy
ASJC Scopus subject areas
- Hardware and Architecture
- Electrical and Electronic Engineering
- Electronic, Optical and Magnetic Materials
- Surfaces, Coatings and Films
- Atomic and Molecular Physics, and Optics