The authors describe the case of a 37-year-old automobile body shop painter, exposed to organic solvents and affected by porphyria cutanea tarda, moderately active chronic hepatitis with intense steatosis and chronic renal insufficiency. The worsening of the renal failure obliged the patient to be submitted to extracorporal dialysis, while the clinical and biochemical symptomatology of the porphyria improved. After one year of dialysis, the patient underwent a kidney transplant. During the year that followed, the patient was well and the porphyrin metabolism became completely normal. It may be hypothesized that the same toxic agent caused the acquired porphyria cutanea tarda, the liver damage and the chronic nephropathy. The signs of the porphyria and chronic hepatitis disappeared once the toxic agents were eliminated and kidney function was restored.
|Translated title of the contribution||Porphyria cutanea tarda and chronic renal failure. Clinical and biochemical recovery after kidney transplant|
|Number of pages||3|
|Journal||Giornale Italiano di Dermatologia e Venereologia|
|Publication status||Published - 1996|
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