TY - JOUR
T1 - Portal hypertensive gastropathy in cirrhotics without varices
T2 - A case-control study
AU - Zardi, Enrico Maria
AU - Ghittoni, Giorgia
AU - Margiotta, Domenico
AU - Viera, Francesca Torello
AU - Di Matteo, Francesco
AU - Rossi, Sandro
PY - 2015/1/11
Y1 - 2015/1/11
N2 - Objective: Information is lacking on portal hypertensive gastropathy (PHG) in cirrhotics without varices; our aim it is to evaluate whether clinical and sonographic parameters are associated with PHG and may provide information suitable for the management of these patients. Patients and methods: After endoscopic selection of 145 cirrhotics without varices, 75 with PHG and 70 without PHG, clinical and sonographic characteristics were assessed. Results: Forty portosystemic shunts were present in 27 patients. The mean Child-Pugh score was 6.3 ± 1.4 and 5.6 ± 0.5 in patients with severe and mild PHG, respectively (P = 0.004). The mean portal vein diameter was 10.4 ± 1.7 and 11.6 ± 2.0 mm in cirrhotics without and with PHG, respectively (P = 0.0002). Conclusion: A link between the presence of PHG and a more advanced phase of cirrhosis was found. Duplex Doppler sonography was confirmed to be a valuable diagnostic method in monitoring cirrhosis. Management of these patients cannot be performed on the basis of a single diagnostic method, and a multimodal diagnostic approach is required.
AB - Objective: Information is lacking on portal hypertensive gastropathy (PHG) in cirrhotics without varices; our aim it is to evaluate whether clinical and sonographic parameters are associated with PHG and may provide information suitable for the management of these patients. Patients and methods: After endoscopic selection of 145 cirrhotics without varices, 75 with PHG and 70 without PHG, clinical and sonographic characteristics were assessed. Results: Forty portosystemic shunts were present in 27 patients. The mean Child-Pugh score was 6.3 ± 1.4 and 5.6 ± 0.5 in patients with severe and mild PHG, respectively (P = 0.004). The mean portal vein diameter was 10.4 ± 1.7 and 11.6 ± 2.0 mm in cirrhotics without and with PHG, respectively (P = 0.0002). Conclusion: A link between the presence of PHG and a more advanced phase of cirrhosis was found. Duplex Doppler sonography was confirmed to be a valuable diagnostic method in monitoring cirrhosis. Management of these patients cannot be performed on the basis of a single diagnostic method, and a multimodal diagnostic approach is required.
KW - Color Doppler ultrasonography
KW - Endoscopy
KW - Gastroesophageal varices
KW - Portal vein
KW - Portosystemic shunts
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U2 - 10.1097/MEG.0000000000000234
DO - 10.1097/MEG.0000000000000234
M3 - Article
C2 - 25386762
AN - SCOPUS:84916877830
VL - 27
SP - 91
EP - 96
JO - European Journal of Gastroenterology and Hepatology
JF - European Journal of Gastroenterology and Hepatology
SN - 0954-691X
IS - 1
ER -