TY - JOUR
T1 - Position paper of the Italian Society for the study of Dementias (Sindem) on the proposal of a new Lexicon on Alzheimer disease
AU - Musicco, Massimo
AU - Padovani, Alessandro
AU - Sorbi, Sandro
AU - Scarpini, Elio
AU - Caffarra, Paolo
AU - Cappa, Stefano
AU - Clerici, Francesca
AU - Tabaton, Massimo
AU - Caltagirone, Carlo
AU - Bonavita, Vincenzo
AU - Bruni, Amalia C.
AU - Bruno, Giuseppe
AU - Federico, Antonio
AU - Ferrarese, Carlo
AU - Marra, Camillo
AU - Nacmias, Benedetta
AU - Parnetti, Lucilla
AU - Pettenati, Carla
AU - Sorrentino, Giuseppe
AU - Tagliavini, Fabrizio
AU - Mariani, Claudio
PY - 2012/2
Y1 - 2012/2
N2 - A panel of Italian neurologists of the Italian Society for the study of Dementias (SINDEM) discussed the recently proposed new lexicon for Alzheimer disease (AD) and the related diagnostic criteria for the different phases of the disease (Preclinical AD, prodromal AD and Alzheimer's dementia) (Dubois et al. in Lancet Neurol 6:734-746, 2007; in Lancet Neurol 9:1118-1127, 2010). The aim of this discussion was to reach a consensus, among the Italian neurologists involved in the study and care of persons with dementia, in particular in reference to the potential use of the proposed diagnostic criteria in clinical practice. After having critically revised the scientific evidence related to the new lexicon and to the new proposed diagnostic criteria, the panel concluded that the proposed new diagnostic criteria and the new proposed lexicon for AD are conceptually attractive. However, the evidence about the instrumental and laboratory markers for the diagnosis of the preclinical and asymptomatic states of the disease are, until to now, insufficient to support the routine clinical use of these investigations.
AB - A panel of Italian neurologists of the Italian Society for the study of Dementias (SINDEM) discussed the recently proposed new lexicon for Alzheimer disease (AD) and the related diagnostic criteria for the different phases of the disease (Preclinical AD, prodromal AD and Alzheimer's dementia) (Dubois et al. in Lancet Neurol 6:734-746, 2007; in Lancet Neurol 9:1118-1127, 2010). The aim of this discussion was to reach a consensus, among the Italian neurologists involved in the study and care of persons with dementia, in particular in reference to the potential use of the proposed diagnostic criteria in clinical practice. After having critically revised the scientific evidence related to the new lexicon and to the new proposed diagnostic criteria, the panel concluded that the proposed new diagnostic criteria and the new proposed lexicon for AD are conceptually attractive. However, the evidence about the instrumental and laboratory markers for the diagnosis of the preclinical and asymptomatic states of the disease are, until to now, insufficient to support the routine clinical use of these investigations.
KW - Alzheimer's disease
KW - Biomarkers
KW - Diagnostic criteria
KW - Expert opinion
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U2 - 10.1007/s10072-011-0825-8
DO - 10.1007/s10072-011-0825-8
M3 - Article
C2 - 22057264
AN - SCOPUS:84863990340
VL - 33
SP - 201
EP - 208
JO - Neurological Sciences
JF - Neurological Sciences
SN - 1590-1874
IS - 1
ER -