TY - JOUR
T1 - Position paper on management of iron deficiency in adult cancer patients
AU - Barni, Sandro
AU - Gascòn, Pere
AU - Petrelli, Fausto
AU - García-Erce, José Antonio
AU - Pedrazzoli, Paolo
AU - Rosti, Giovanni
AU - Giordano, Giulio
AU - Mafodda, Antonio
AU - Múñoz, Manuel
PY - 2017/8/3
Y1 - 2017/8/3
N2 - Introduction: Disorders of iron metabolism are commonly seen in onco-hematological clinical practice. Iron-deficiency anemia and cancer-associated anemia are usually treated with supportive therapies. Optimal management of these conditions are discussed in this perspective paper. Areas covered: A position paper discussing a number of hot topics on anemia in cancer patients is presented. The main areas covered by experts in the field are: definitions, prevalence and consequences of anemia and iron deficiency, incidence of anemia resulting from targeted therapies, importance of anemia diagnosis and monitoring, evaluation of iron status before and during treatment, role of transfusions and erythropoiesis-stimulating agents, management of iron deficiency with or without anemia, parenteral iron supplementation, role of new oral iron formulations, safety and cost issues regarding different iron compounds and administration routes. Expert commentary: Despite the availability of newer therapeutic options for its management, anemia still represents a major complication of treatment in cancer patients (surgery, chemotherapy, radiotherapy, targeted therapies), aggravating physical impairment, and negatively affecting general outcome. The view expressed by the panelists, attendees of the 4th Mediterranean Course on Iron Anemia, summarizes what they consider optimal clinical practice for screening, diagnosis, treatment and monitoring of iron deficiency and anemia in cancer patients.
AB - Introduction: Disorders of iron metabolism are commonly seen in onco-hematological clinical practice. Iron-deficiency anemia and cancer-associated anemia are usually treated with supportive therapies. Optimal management of these conditions are discussed in this perspective paper. Areas covered: A position paper discussing a number of hot topics on anemia in cancer patients is presented. The main areas covered by experts in the field are: definitions, prevalence and consequences of anemia and iron deficiency, incidence of anemia resulting from targeted therapies, importance of anemia diagnosis and monitoring, evaluation of iron status before and during treatment, role of transfusions and erythropoiesis-stimulating agents, management of iron deficiency with or without anemia, parenteral iron supplementation, role of new oral iron formulations, safety and cost issues regarding different iron compounds and administration routes. Expert commentary: Despite the availability of newer therapeutic options for its management, anemia still represents a major complication of treatment in cancer patients (surgery, chemotherapy, radiotherapy, targeted therapies), aggravating physical impairment, and negatively affecting general outcome. The view expressed by the panelists, attendees of the 4th Mediterranean Course on Iron Anemia, summarizes what they consider optimal clinical practice for screening, diagnosis, treatment and monitoring of iron deficiency and anemia in cancer patients.
KW - anemia
KW - Cancer
KW - consensus
KW - erythropoiesis-stimulating agents
KW - iron deficiency
KW - iron therapy
KW - sucrosomial iron
KW - transfusion
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U2 - 10.1080/17474086.2017.1343140
DO - 10.1080/17474086.2017.1343140
M3 - Article
C2 - 28656800
AN - SCOPUS:85021827199
VL - 10
SP - 685
EP - 695
JO - Expert Review of Hematology
JF - Expert Review of Hematology
SN - 1747-4086
IS - 8
ER -