Positive surgical margins after robotic assisted radical prostatectomy

A multi-institutional study

Vipul R. Patel, Rafael F. Coelho, Bernardo Rocco, Marcelo Orvieto, Ananthakrishnan Sivaraman, Kenneth J. Palmer, Darien Kameh, Luigi Santoro, Geoff D. Coughlin, Michael Liss, Wooju Jeong, John Malcolm, Joshua M. Stern, Saurabh Sharma, Kevin C. Zorn, Sergey Shikanov, Arieh L. Shalhav, Gregory P. Zagaja, Thomas E. Ahlering, Koon H. Rha & 4 others David M. Albala, Michael D. Fabrizio, David I. Lee, Sanket Chauhan

Research output: Contribution to journalArticle

79 Citations (Scopus)

Abstract

Purpose: Positive surgical margins are an independent predictive factor for biochemical recurrence after radical prostatectomy. We analyzed the incidence of and associative factors for positive surgical margins in a multi-institutional series of 8,418 robotic assisted radical prostatectomies. Materials and Methods: We analyzed the records of 8,418 patients who underwent robotic assisted radical prostatectomy at 7 institutions. Of the patients 323 had missing data on margin status. Positive surgical margins were categorized into 4 groups, including apex, bladder neck, posterolateral and multifocal. The records of 6,169 patients were available for multivariate analysis. The variables entered into the logistic regression models were age, body mass index, preoperative prostate specific antigen, biopsy Gleason score, prostate weight and pathological stage. A second model was built to identify predictive factors for positive surgical margins in the subset of patients with organ confined disease (pT2). Results: The overall positive surgical margin rate was 15.7% (1,272 of 8,095 patients). The positive surgical margin rate for pT2 and pT3 disease was 9.45% and 37.2%, respectively. On multivariate analysis pathological stage (pT2 vs pT3 OR 4.588, p

Original languageEnglish
Pages (from-to)511-516
Number of pages6
JournalJournal of Urology
Volume186
Issue number2
DOIs
Publication statusPublished - Aug 2011

Fingerprint

Robotics
Prostatectomy
Multivariate Analysis
Logistic Models
Neoplasm Grading
Prostate-Specific Antigen
Margins of Excision
Prostate
Urinary Bladder
Body Mass Index
Biopsy
Weights and Measures
Recurrence
Incidence

Keywords

  • local
  • neoplasm recurrence
  • prostate
  • prostatectomy
  • prostatic neoplasms
  • robotics

ASJC Scopus subject areas

  • Urology

Cite this

Patel, V. R., Coelho, R. F., Rocco, B., Orvieto, M., Sivaraman, A., Palmer, K. J., ... Chauhan, S. (2011). Positive surgical margins after robotic assisted radical prostatectomy: A multi-institutional study. Journal of Urology, 186(2), 511-516. https://doi.org/10.1016/j.juro.2011.03.112

Positive surgical margins after robotic assisted radical prostatectomy : A multi-institutional study. / Patel, Vipul R.; Coelho, Rafael F.; Rocco, Bernardo; Orvieto, Marcelo; Sivaraman, Ananthakrishnan; Palmer, Kenneth J.; Kameh, Darien; Santoro, Luigi; Coughlin, Geoff D.; Liss, Michael; Jeong, Wooju; Malcolm, John; Stern, Joshua M.; Sharma, Saurabh; Zorn, Kevin C.; Shikanov, Sergey; Shalhav, Arieh L.; Zagaja, Gregory P.; Ahlering, Thomas E.; Rha, Koon H.; Albala, David M.; Fabrizio, Michael D.; Lee, David I.; Chauhan, Sanket.

In: Journal of Urology, Vol. 186, No. 2, 08.2011, p. 511-516.

Research output: Contribution to journalArticle

Patel, VR, Coelho, RF, Rocco, B, Orvieto, M, Sivaraman, A, Palmer, KJ, Kameh, D, Santoro, L, Coughlin, GD, Liss, M, Jeong, W, Malcolm, J, Stern, JM, Sharma, S, Zorn, KC, Shikanov, S, Shalhav, AL, Zagaja, GP, Ahlering, TE, Rha, KH, Albala, DM, Fabrizio, MD, Lee, DI & Chauhan, S 2011, 'Positive surgical margins after robotic assisted radical prostatectomy: A multi-institutional study', Journal of Urology, vol. 186, no. 2, pp. 511-516. https://doi.org/10.1016/j.juro.2011.03.112
Patel, Vipul R. ; Coelho, Rafael F. ; Rocco, Bernardo ; Orvieto, Marcelo ; Sivaraman, Ananthakrishnan ; Palmer, Kenneth J. ; Kameh, Darien ; Santoro, Luigi ; Coughlin, Geoff D. ; Liss, Michael ; Jeong, Wooju ; Malcolm, John ; Stern, Joshua M. ; Sharma, Saurabh ; Zorn, Kevin C. ; Shikanov, Sergey ; Shalhav, Arieh L. ; Zagaja, Gregory P. ; Ahlering, Thomas E. ; Rha, Koon H. ; Albala, David M. ; Fabrizio, Michael D. ; Lee, David I. ; Chauhan, Sanket. / Positive surgical margins after robotic assisted radical prostatectomy : A multi-institutional study. In: Journal of Urology. 2011 ; Vol. 186, No. 2. pp. 511-516.
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AU - Sivaraman, Ananthakrishnan

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