Abstract
Purpose: Positive surgical margins are an independent predictive factor for biochemical recurrence after radical prostatectomy. We analyzed the incidence of and associative factors for positive surgical margins in a multi-institutional series of 8,418 robotic assisted radical prostatectomies. Materials and Methods: We analyzed the records of 8,418 patients who underwent robotic assisted radical prostatectomy at 7 institutions. Of the patients 323 had missing data on margin status. Positive surgical margins were categorized into 4 groups, including apex, bladder neck, posterolateral and multifocal. The records of 6,169 patients were available for multivariate analysis. The variables entered into the logistic regression models were age, body mass index, preoperative prostate specific antigen, biopsy Gleason score, prostate weight and pathological stage. A second model was built to identify predictive factors for positive surgical margins in the subset of patients with organ confined disease (pT2). Results: The overall positive surgical margin rate was 15.7% (1,272 of 8,095 patients). The positive surgical margin rate for pT2 and pT3 disease was 9.45% and 37.2%, respectively. On multivariate analysis pathological stage (pT2 vs pT3 OR 4.588, p
| Original language | English |
|---|---|
| Pages (from-to) | 511-516 |
| Number of pages | 6 |
| Journal | Journal of Urology |
| Volume | 186 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Aug 2011 |
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Keywords
- local
- neoplasm recurrence
- prostate
- prostatectomy
- prostatic neoplasms
- robotics
ASJC Scopus subject areas
- Urology
Cite this
Positive surgical margins after robotic assisted radical prostatectomy : A multi-institutional study. / Patel, Vipul R.; Coelho, Rafael F.; Rocco, Bernardo; Orvieto, Marcelo; Sivaraman, Ananthakrishnan; Palmer, Kenneth J.; Kameh, Darien; Santoro, Luigi; Coughlin, Geoff D.; Liss, Michael; Jeong, Wooju; Malcolm, John; Stern, Joshua M.; Sharma, Saurabh; Zorn, Kevin C.; Shikanov, Sergey; Shalhav, Arieh L.; Zagaja, Gregory P.; Ahlering, Thomas E.; Rha, Koon H.; Albala, David M.; Fabrizio, Michael D.; Lee, David I.; Chauhan, Sanket.
In: Journal of Urology, Vol. 186, No. 2, 08.2011, p. 511-516.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Positive surgical margins after robotic assisted radical prostatectomy
T2 - A multi-institutional study
AU - Patel, Vipul R.
AU - Coelho, Rafael F.
AU - Rocco, Bernardo
AU - Orvieto, Marcelo
AU - Sivaraman, Ananthakrishnan
AU - Palmer, Kenneth J.
AU - Kameh, Darien
AU - Santoro, Luigi
AU - Coughlin, Geoff D.
AU - Liss, Michael
AU - Jeong, Wooju
AU - Malcolm, John
AU - Stern, Joshua M.
AU - Sharma, Saurabh
AU - Zorn, Kevin C.
AU - Shikanov, Sergey
AU - Shalhav, Arieh L.
AU - Zagaja, Gregory P.
AU - Ahlering, Thomas E.
AU - Rha, Koon H.
AU - Albala, David M.
AU - Fabrizio, Michael D.
AU - Lee, David I.
AU - Chauhan, Sanket
PY - 2011/8
Y1 - 2011/8
N2 - Purpose: Positive surgical margins are an independent predictive factor for biochemical recurrence after radical prostatectomy. We analyzed the incidence of and associative factors for positive surgical margins in a multi-institutional series of 8,418 robotic assisted radical prostatectomies. Materials and Methods: We analyzed the records of 8,418 patients who underwent robotic assisted radical prostatectomy at 7 institutions. Of the patients 323 had missing data on margin status. Positive surgical margins were categorized into 4 groups, including apex, bladder neck, posterolateral and multifocal. The records of 6,169 patients were available for multivariate analysis. The variables entered into the logistic regression models were age, body mass index, preoperative prostate specific antigen, biopsy Gleason score, prostate weight and pathological stage. A second model was built to identify predictive factors for positive surgical margins in the subset of patients with organ confined disease (pT2). Results: The overall positive surgical margin rate was 15.7% (1,272 of 8,095 patients). The positive surgical margin rate for pT2 and pT3 disease was 9.45% and 37.2%, respectively. On multivariate analysis pathological stage (pT2 vs pT3 OR 4.588, p
AB - Purpose: Positive surgical margins are an independent predictive factor for biochemical recurrence after radical prostatectomy. We analyzed the incidence of and associative factors for positive surgical margins in a multi-institutional series of 8,418 robotic assisted radical prostatectomies. Materials and Methods: We analyzed the records of 8,418 patients who underwent robotic assisted radical prostatectomy at 7 institutions. Of the patients 323 had missing data on margin status. Positive surgical margins were categorized into 4 groups, including apex, bladder neck, posterolateral and multifocal. The records of 6,169 patients were available for multivariate analysis. The variables entered into the logistic regression models were age, body mass index, preoperative prostate specific antigen, biopsy Gleason score, prostate weight and pathological stage. A second model was built to identify predictive factors for positive surgical margins in the subset of patients with organ confined disease (pT2). Results: The overall positive surgical margin rate was 15.7% (1,272 of 8,095 patients). The positive surgical margin rate for pT2 and pT3 disease was 9.45% and 37.2%, respectively. On multivariate analysis pathological stage (pT2 vs pT3 OR 4.588, p
KW - local
KW - neoplasm recurrence
KW - prostate
KW - prostatectomy
KW - prostatic neoplasms
KW - robotics
UR - http://www.scopus.com/inward/record.url?scp=79960171435&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79960171435&partnerID=8YFLogxK
U2 - 10.1016/j.juro.2011.03.112
DO - 10.1016/j.juro.2011.03.112
M3 - Article
VL - 186
SP - 511
EP - 516
JO - Journal of Urology
JF - Journal of Urology
SN - 0022-5347
IS - 2
ER -