TY - JOUR
T1 - Positive trend in survival to hospital discharge after out-of-hospital cardiac arrest
T2 - A quantitative review of the literature
AU - Savastano, Simone
AU - Klersy, Catherine
AU - Raimondi, Maurizio
AU - Langord, Karen
AU - Vanni, Vincenzo
AU - Rordorf, Roberto
AU - Vicentini, Alessandro
AU - Petracci, Barbara
AU - Landolina, Maurizio
AU - Visconti, Luigi Oltrona
PY - 2014
Y1 - 2014
N2 - Background Seven editions of cardiopulmonary resuscitation (CPR) and emergency cardiovascular care guidelines have been published with many changes, in particular, about CPR. Objectives The aim of our study was to evaluate the temporal trend of survival to hospital discharge after out-ofhospital cardiac arrest (OHCA) as a possible effect of guidelines changes. Methods We searched PubMed for observational studies on 'survival to hospital discharge after OHCA'. Survival to discharge was the primary outcome; prehospital return of spontaneous circulation and survival to hospital admission were our secondary endpoints. All data were analyzed according to the year of inclusion: group 1 before 2000; group 2 between 2000 and 2005; and group 3 after 2005. Mortality rates were compared between groups by means of a group frequencyweighted log-linear model. Results We considered 38 of 201 studies for a total of 156 301 patients. Survival to hospital discharge rate was 5.0% [95% confidence interval (CI) 4.9-5.2) in group 1; 6.1% (95% CI 5.9-6.4) in group 2; and 9.1% (95% CI 8.9-9.4) in group 3 (P
AB - Background Seven editions of cardiopulmonary resuscitation (CPR) and emergency cardiovascular care guidelines have been published with many changes, in particular, about CPR. Objectives The aim of our study was to evaluate the temporal trend of survival to hospital discharge after out-ofhospital cardiac arrest (OHCA) as a possible effect of guidelines changes. Methods We searched PubMed for observational studies on 'survival to hospital discharge after OHCA'. Survival to discharge was the primary outcome; prehospital return of spontaneous circulation and survival to hospital admission were our secondary endpoints. All data were analyzed according to the year of inclusion: group 1 before 2000; group 2 between 2000 and 2005; and group 3 after 2005. Mortality rates were compared between groups by means of a group frequencyweighted log-linear model. Results We considered 38 of 201 studies for a total of 156 301 patients. Survival to hospital discharge rate was 5.0% [95% confidence interval (CI) 4.9-5.2) in group 1; 6.1% (95% CI 5.9-6.4) in group 2; and 9.1% (95% CI 8.9-9.4) in group 3 (P
KW - cardiac arrest
KW - cardiopulmonary resuscitation
KW - guidelines
KW - survival
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U2 - 10.2459/JCM.0000000000000040
DO - 10.2459/JCM.0000000000000040
M3 - Article
C2 - 24978661
AN - SCOPUS:84903819039
VL - 15
SP - 609
EP - 615
JO - Journal of Cardiovascular Medicine
JF - Journal of Cardiovascular Medicine
SN - 1558-2027
IS - 8
ER -