TY - JOUR
T1 - Positron emission tomography with computed tomography imaging (PET/CT) for the radiotherapy planning definition of the biological target volume
T2 - PART 2
AU - AIRO Giovani - Italian Association of Radiation Oncology-Young Members and AIMN -Italian Association of Nuclear Medicine- Young Members Working Group
AU - Fiorentino, Alba
AU - Laudicella, Riccardo
AU - Ciurlia, Elisa
AU - Annunziata, Salvatore
AU - Lancellotta, Valentina
AU - Mapelli, Paola
AU - Tuscano, Carmelo
AU - Caobelli, Federico
AU - Evangelista, Laura
AU - Marino, Lorenza
AU - Quartuccio, Natale
AU - Fiore, Michele
AU - Borghetti, Paolo
AU - Chiaravalloti, Agostino
AU - Ricci, Maria
AU - Desideri, Isacco
AU - Alongi, Pierpaolo
N1 - Copyright © 2019 Elsevier B.V. All rights reserved.
PY - 2019/7
Y1 - 2019/7
N2 - AIM: Positron Emission Tomography with Computed Tomography (PET/CT) has been proven to be useful in the definition of Radiotherapy (RT) target volume. In this regard, the present expert review summarizes existing data for pancreas, prostate, gynecological and rectum/anal cancer.METHODS: A comprehensive search of published original article was made, based on SCOPUS and PubMed database, selecting the paper that evaluated the role of PET/CT in the definition of RT volume.RESULTS: FDG-PET has an important and promising role for pancreatic cancer. Choline PET/CT could be useful for identifying high-risk volumes for prostate cancer; while PSMA PET/CT is still under evaluation. FDG PET/CT in gynecological cancers has been shown to impact external-beam RT planning. The role of FDG-PET for Gross Tumor volume identification is crucial, representing a useful and powerful tool for anal and rectal cancer.CONCLUSION: Taken together, molecular and functional imaging approaches offer a major step to individualize radiotherapeutic approach.
AB - AIM: Positron Emission Tomography with Computed Tomography (PET/CT) has been proven to be useful in the definition of Radiotherapy (RT) target volume. In this regard, the present expert review summarizes existing data for pancreas, prostate, gynecological and rectum/anal cancer.METHODS: A comprehensive search of published original article was made, based on SCOPUS and PubMed database, selecting the paper that evaluated the role of PET/CT in the definition of RT volume.RESULTS: FDG-PET has an important and promising role for pancreatic cancer. Choline PET/CT could be useful for identifying high-risk volumes for prostate cancer; while PSMA PET/CT is still under evaluation. FDG PET/CT in gynecological cancers has been shown to impact external-beam RT planning. The role of FDG-PET for Gross Tumor volume identification is crucial, representing a useful and powerful tool for anal and rectal cancer.CONCLUSION: Taken together, molecular and functional imaging approaches offer a major step to individualize radiotherapeutic approach.
KW - Humans
KW - Image Processing, Computer-Assisted/methods
KW - Neoplasms/diagnostic imaging
KW - Positron Emission Tomography Computed Tomography/methods
KW - Radiotherapy Planning, Computer-Assisted/methods
KW - Radiotherapy, Image-Guided/methods
U2 - 10.1016/j.critrevonc.2019.03.008
DO - 10.1016/j.critrevonc.2019.03.008
M3 - Review article
C2 - 30940428
VL - 139
SP - 117
EP - 124
JO - Critical Reviews in Oncology/Hematology
JF - Critical Reviews in Oncology/Hematology
SN - 1040-8428
ER -