Positron emission tomography with computed tomography imaging (PET/CT) for the radiotherapy planning definition of the biological target volume: PART 2

AIRO Giovani - Italian Association of Radiation Oncology-Young Members and AIMN -Italian Association of Nuclear Medicine- Young Members Working Group

Research output: Contribution to journalReview article

Abstract

AIM: Positron Emission Tomography with Computed Tomography (PET/CT) has been proven to be useful in the definition of Radiotherapy (RT) target volume. In this regard, the present expert review summarizes existing data for pancreas, prostate, gynecological and rectum/anal cancer.

METHODS: A comprehensive search of published original article was made, based on SCOPUS and PubMed database, selecting the paper that evaluated the role of PET/CT in the definition of RT volume.

RESULTS: FDG-PET has an important and promising role for pancreatic cancer. Choline PET/CT could be useful for identifying high-risk volumes for prostate cancer; while PSMA PET/CT is still under evaluation. FDG PET/CT in gynecological cancers has been shown to impact external-beam RT planning. The role of FDG-PET for Gross Tumor volume identification is crucial, representing a useful and powerful tool for anal and rectal cancer.

CONCLUSION: Taken together, molecular and functional imaging approaches offer a major step to individualize radiotherapeutic approach.

Original languageEnglish
Pages (from-to)117-124
Number of pages8
JournalCritical Reviews in Oncology/Hematology
Volume139
DOIs
Publication statusPublished - Jul 2019

Keywords

  • Humans
  • Image Processing, Computer-Assisted/methods
  • Neoplasms/diagnostic imaging
  • Positron Emission Tomography Computed Tomography/methods
  • Radiotherapy Planning, Computer-Assisted/methods
  • Radiotherapy, Image-Guided/methods

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    AIRO Giovani - Italian Association of Radiation Oncology-Young Members and AIMN -Italian Association of Nuclear Medicine- Young Members Working Group (2019). Positron emission tomography with computed tomography imaging (PET/CT) for the radiotherapy planning definition of the biological target volume: PART 2. Critical Reviews in Oncology/Hematology, 139, 117-124. https://doi.org/10.1016/j.critrevonc.2019.03.008