Positron emission tomography with computed tomography imaging (PET/CT) for the radiotherapy planning definition of the biological target volume: PART 2

AIRO Giovani - Italian Association of Radiation Oncology-Young Members, AIMN -Italian Association of Nuclear Medicine- Young Members Working Group, Alba Fiorentino, Riccardo Laudicella, Elisa Ciurlia, Salvatore Annunziata, Valentina Lancellotta, Paola Mapelli, Carmelo Tuscano, Federico Caobelli, Laura Evangelista, Lorenza Marino, Natale Quartuccio, Michele Fiore, Paolo Borghetti, Agostino Chiaravalloti, Maria Ricci, Isacco Desideri, Pierpaolo Alongi

Research output: Contribution to journalArticle

Abstract

AIM: Positron Emission Tomography with Computed Tomography (PET/CT) has been proven to be useful in the definition of Radiotherapy (RT) target volume. In this regard, the present expert review summarizes existing data for pancreas, prostate, gynecological and rectum/anal cancer.METHODS: A comprehensive search of published original article was made, based on SCOPUS and PubMed database, selecting the paper that evaluated the role of PET/CT in the definition of RT volume.RESULTS: FDG-PET has an important and promising role for pancreatic cancer. Choline PET/CT could be useful for identifying high-risk volumes for prostate cancer; while PSMA PET/CT is still under evaluation. FDG PET/CT in gynecological cancers has been shown to impact external-beam RT planning. The role of FDG-PET for Gross Tumor volume identification is crucial, representing a useful and powerful tool for anal and rectal cancer.CONCLUSION: Taken together, molecular and functional imaging approaches offer a major step to individualize radiotherapeutic approach.
Original languageEnglish
Pages (from-to)117-124
Number of pages8
JournalCritical Reviews in Oncology/Hematology
Volume139
DOIs
Publication statusPublished - Jul 1 2019

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Keywords

  • Humans
  • Image Processing
  • Computer-Assisted/methods
  • Neoplasms/diagnostic imaging
  • Positron Emission Tomography Computed Tomography/methods
  • Radiotherapy Planning
  • Radiotherapy
  • Image-Guided/methods

Cite this

Members, AIRO. G. . I. A. O. R. O-Y., Group, AIMN. -I. A. O. N. M. Y. M. W., Fiorentino, A., Laudicella, R., Ciurlia, E., Annunziata, S., Lancellotta, V., Mapelli, P., Tuscano, C., Caobelli, F., Evangelista, L., Marino, L., Quartuccio, N., Fiore, M., Borghetti, P., Chiaravalloti, A., Ricci, M., Desideri, I., & Alongi, P. (2019). Positron emission tomography with computed tomography imaging (PET/CT) for the radiotherapy planning definition of the biological target volume: PART 2. Critical Reviews in Oncology/Hematology, 139, 117-124. https://doi.org/10.1016/j.critrevonc.2019.03.008