Abstract
Purpose: Amnestic syndromes are acknowledged to be associated to bilateral hippocampal damage. Materials and methods: We briefly report the case of a young man who underwent anterior left temporal lobectomy for a medically refractory temporal lobe epilepsy due to hippocampal sclerosis with an excellent seizure and neuropsychological outcome. Approximately 10 years later, he presented with a subacute severe global amnesia and neuroimaging findings of a damage involving the contralateral mesial temporal lobe structures. Results: A diagnosis of a possible autoimmune encephalitis was made. Conclusions: Due to its peculiarities (compared with other cases of bilateral temporal lesions, the damage occurred on two distinct occasions), this case might contribute to shed light on the issue of the possible contralateral reorganization of memory processes subserved by the mesial temporal lobe structures chronically involved in epileptogenesis.
| Original language | English |
|---|---|
| Pages (from-to) | 464-466 |
| Number of pages | 3 |
| Journal | International Journal of Neuroscience |
| Volume | 128 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - May 1 2018 |
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Keywords
- anterior temporal lobectomy
- global amnesia
- limbic encephalitis
- memory
- Temporal lobe epilepsy
ASJC Scopus subject areas
- Neuroscience(all)
Cite this
Possible autoantibody-negative limbic encephalitis after anterior temporal lobectomy for hippocampal sclerosis. / Casciato, Sara; D'Aniello, Alfredo; Mascia, Addolorata; Quarato, Pier Paolo; De Risi, Marco; Grammaldo, Liliana G.; Esposito, Vincenzo; Zoccarato, Marco; Di Gennaro, Giancarlo.
In: International Journal of Neuroscience, Vol. 128, No. 5, 01.05.2018, p. 464-466.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Possible autoantibody-negative limbic encephalitis after anterior temporal lobectomy for hippocampal sclerosis
AU - Casciato, Sara
AU - D'Aniello, Alfredo
AU - Mascia, Addolorata
AU - Quarato, Pier Paolo
AU - De Risi, Marco
AU - Grammaldo, Liliana G.
AU - Esposito, Vincenzo
AU - Zoccarato, Marco
AU - Di Gennaro, Giancarlo
PY - 2018/5/1
Y1 - 2018/5/1
N2 - Purpose: Amnestic syndromes are acknowledged to be associated to bilateral hippocampal damage. Materials and methods: We briefly report the case of a young man who underwent anterior left temporal lobectomy for a medically refractory temporal lobe epilepsy due to hippocampal sclerosis with an excellent seizure and neuropsychological outcome. Approximately 10 years later, he presented with a subacute severe global amnesia and neuroimaging findings of a damage involving the contralateral mesial temporal lobe structures. Results: A diagnosis of a possible autoimmune encephalitis was made. Conclusions: Due to its peculiarities (compared with other cases of bilateral temporal lesions, the damage occurred on two distinct occasions), this case might contribute to shed light on the issue of the possible contralateral reorganization of memory processes subserved by the mesial temporal lobe structures chronically involved in epileptogenesis.
AB - Purpose: Amnestic syndromes are acknowledged to be associated to bilateral hippocampal damage. Materials and methods: We briefly report the case of a young man who underwent anterior left temporal lobectomy for a medically refractory temporal lobe epilepsy due to hippocampal sclerosis with an excellent seizure and neuropsychological outcome. Approximately 10 years later, he presented with a subacute severe global amnesia and neuroimaging findings of a damage involving the contralateral mesial temporal lobe structures. Results: A diagnosis of a possible autoimmune encephalitis was made. Conclusions: Due to its peculiarities (compared with other cases of bilateral temporal lesions, the damage occurred on two distinct occasions), this case might contribute to shed light on the issue of the possible contralateral reorganization of memory processes subserved by the mesial temporal lobe structures chronically involved in epileptogenesis.
KW - anterior temporal lobectomy
KW - global amnesia
KW - limbic encephalitis
KW - memory
KW - Temporal lobe epilepsy
UR - http://www.scopus.com/inward/record.url?scp=85034225381&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85034225381&partnerID=8YFLogxK
U2 - 10.1080/00207454.2017.1394852
DO - 10.1080/00207454.2017.1394852
M3 - Article
AN - SCOPUS:85034225381
VL - 128
SP - 464
EP - 466
JO - International Journal of Neuroscience
JF - International Journal of Neuroscience
SN - 0020-7454
IS - 5
ER -