Possible linkage between primary affective disorder susceptibility locus and HLA haplotypes

E. Smeraldi, L. Bellodi

Research output: Contribution to journalArticlepeer-review

Abstract

The authors analyzed the concordance of sib pairs for HLA typing in cases where both sibs had affective illness and where the sibs were discordant. They detected an excess of HLA similarities in doubly affected sibs and a lack of similarities in discordant sibs. Therefore, the authors hypothesize that HLA may be linked with a primary affective disorder susceptibility locus or it may be associated with such a locus in some other way.

Original languageEnglish
Pages (from-to)1232-1234
Number of pages3
JournalAmerican Journal of Psychiatry
Volume138
Issue number9
Publication statusPublished - 1981

ASJC Scopus subject areas

  • Psychiatry and Mental health

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