Objective: Major depressive disorder (MDD) is a common, recurrent disorder that requires long-term management. Adequate acute phase treatment of MDD is essential to reduce symptomatology and to improve the quality of life and the clinical course of illness. After remission, pharmacological treatment should be continued for 4-9 months to consolidate the remission and to prevent relapse. Literature data support the effect of psychoeducational therapy associated to pharmacological intervention also during the acute treatment of major depressive episode, having as primary objective the management of cognitive dysfunction, that is an important relapse risk factor. The aim of the present study is to describe the form of involvement with a weekly group psychoeducational therapy in hospitalized patients in Mood Disorder Unit of San Raffaele-Turro Hospital in Milan, and to verify the possibly role of this additional treatment strategy on relapse prevention during a 9-months follow-up period. Methods: Mood Disorder Unit of San Raffaele-Turro Hospital in Milan consists of nurses, psychiatrists, psychologists and professional educators. Sample includes 85 patients hospitalized for a major depressive episode (DSM-IV). When they achieved the almost complete remission of their depressive symptomatology according to clinical judgement, their psychiatrist proposed them to take part to a group psychoeducational session conducted by components of whole team once a week. Their involvement with group psychoeducational sessions was assessed by professional educators using a rating instrument created on purpose At discharge, patients filled in a "self administered satisfaction questionnaire" specific for psychoeducation and WHOQOl to assess the perceived quality of their life. They remained in continuation treatment as outpatients for 9 months. We applied survival analyses and regression models considering relapse and re-hospitalization as dependent variables. Results: Data collected from "satisfaction questionnaire" indicated patient's high satisfaction about group psychotherapy (Figs. 1, 2). All patients maintained the compliance to pharmacological treatment and to the monthly clinical evaluation with their psychiatrist. At the end of follow-up period, 40% of the sample relapsed (Fig. 4). All clinical and social variables as well as the scores of the above-mentioned rating instruments were analyzed with of survival analysis to identify the ones that were possibly related to the risk of relapse. Among all the analyzed variables, patient's "coherence", "interest", and "processing of information" during therapy group and WHOQOL scores in "physical" and "environmental" areas were significantly related to the risk of relapse and re-hospitalization (Table 111). Conclusion: These results are an encouraging evidence of the cognitive support role of group psychoeducational therapy also during the acute treatment of depression and patient's form of involvement with the group therapy could be considered as a long-term normothymia predictor.
|Translated title of the contribution||Possible role in relapse prevention of the quality of participation in psychoeducational therapy combined with acute antidepressant treatment|
|Number of pages||9|
|Journal||Italian Journal of Psychopathology|
|Publication status||Published - Dec 2007|
ASJC Scopus subject areas
- Psychiatry and Mental health