Post-inflammatory retinal dystrophy in CINCA syndrome

Donato Rigante, Achille Stabile, Angelo Minnella, Laura Avallone, Lucia Ziccardi, Giulia Bersani, Giovanna Stifano, Adele Compagnone, Benedetto Falsini

Research output: Contribution to journalArticle

Abstract

Right chorioretinitis and bilateral pseudopapilledema were firstly appreciated in a 9-month-old child with neonatal findings of aseptic chronic meningitis, framed in the context of CINCA syndrome at 1 year. Therapeutical response to various combinations of drugs was inconsistent until 7 years, when anakinra was started with immediate clinical and laboratory improvement. A state of severe retinal dystrophy of post-inflammatory origin became evident on funduscopy, optical coherence tomography and visual electrophysiology tests at the age of 10 years, which remained stationary after 1 year of anakinra treatment.

Original languageEnglish
Pages (from-to)389-393
Number of pages5
JournalRheumatology International
Volume30
Issue number3
DOIs
Publication statusPublished - Jan 2010

Fingerprint

Cryopyrin-Associated Periodic Syndromes
Retinal Dystrophies
Interleukin 1 Receptor Antagonist Protein
Chorioretinitis
Aseptic Meningitis
Electrophysiology
Optical Coherence Tomography
Drug Combinations
Therapeutics

Keywords

  • CINCA syndrome
  • Retinal dystrophy

ASJC Scopus subject areas

  • Rheumatology
  • Immunology
  • Immunology and Allergy

Cite this

Rigante, D., Stabile, A., Minnella, A., Avallone, L., Ziccardi, L., Bersani, G., ... Falsini, B. (2010). Post-inflammatory retinal dystrophy in CINCA syndrome. Rheumatology International, 30(3), 389-393. https://doi.org/10.1007/s00296-009-0939-y

Post-inflammatory retinal dystrophy in CINCA syndrome. / Rigante, Donato; Stabile, Achille; Minnella, Angelo; Avallone, Laura; Ziccardi, Lucia; Bersani, Giulia; Stifano, Giovanna; Compagnone, Adele; Falsini, Benedetto.

In: Rheumatology International, Vol. 30, No. 3, 01.2010, p. 389-393.

Research output: Contribution to journalArticle

Rigante, D, Stabile, A, Minnella, A, Avallone, L, Ziccardi, L, Bersani, G, Stifano, G, Compagnone, A & Falsini, B 2010, 'Post-inflammatory retinal dystrophy in CINCA syndrome', Rheumatology International, vol. 30, no. 3, pp. 389-393. https://doi.org/10.1007/s00296-009-0939-y
Rigante D, Stabile A, Minnella A, Avallone L, Ziccardi L, Bersani G et al. Post-inflammatory retinal dystrophy in CINCA syndrome. Rheumatology International. 2010 Jan;30(3):389-393. https://doi.org/10.1007/s00296-009-0939-y
Rigante, Donato ; Stabile, Achille ; Minnella, Angelo ; Avallone, Laura ; Ziccardi, Lucia ; Bersani, Giulia ; Stifano, Giovanna ; Compagnone, Adele ; Falsini, Benedetto. / Post-inflammatory retinal dystrophy in CINCA syndrome. In: Rheumatology International. 2010 ; Vol. 30, No. 3. pp. 389-393.
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