Post-radiation gliomas

M. Salvati, F. Puzzilli, R. Bristot, L. Cervoni

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Aims and background: Radiotherapy is important in the treatment of neoplasm of the central nervous system, but various side efects, particularly neoplastic, have been described. Recently, post-radiation gliomas have been reported. Methods: The authors review 88 cases of cerebral glioma following radiotherapy in patients operated for neoplasms of the nervous system, including 6 personal cases of post-radiation gliomas treated in the Neurosurgical Division of the Department ot Neurological Sciences, 'La Sapienza' University, Rome. The criteria used to define this unusual pathologic association are discussed. Results: There was a male predominance. Post-radiation gliomas were particularly malignant, the average dose was 33 Gy, and average free latency was 9.6 years. The first disease was most frequently acute lymphatic leukemia. Conclusions: Post-radiation gliomas have particular features but do not present a histologic or clinical behavior different from analogous spontaneous gliomas. The fact that 88 cases have been reported in recent years suggests that a thorough biological, clinical study be carried out on this association.

Original languageEnglish
Pages (from-to)220-223
Number of pages4
JournalTumori
Volume80
Issue number3
Publication statusPublished - 1994

Fingerprint

Glioma
Radiation
Radiotherapy
Nervous System Neoplasms
Central Nervous System Neoplasms
Leukemia

Keywords

  • astrocytoma
  • glioblastoma
  • radiation-induced tumor

ASJC Scopus subject areas

  • Cancer Research

Cite this

Salvati, M., Puzzilli, F., Bristot, R., & Cervoni, L. (1994). Post-radiation gliomas. Tumori, 80(3), 220-223.

Post-radiation gliomas. / Salvati, M.; Puzzilli, F.; Bristot, R.; Cervoni, L.

In: Tumori, Vol. 80, No. 3, 1994, p. 220-223.

Research output: Contribution to journalArticle

Salvati, M, Puzzilli, F, Bristot, R & Cervoni, L 1994, 'Post-radiation gliomas', Tumori, vol. 80, no. 3, pp. 220-223.
Salvati M, Puzzilli F, Bristot R, Cervoni L. Post-radiation gliomas. Tumori. 1994;80(3):220-223.
Salvati, M. ; Puzzilli, F. ; Bristot, R. ; Cervoni, L. / Post-radiation gliomas. In: Tumori. 1994 ; Vol. 80, No. 3. pp. 220-223.
@article{afe3eac8df954a568c9b3e140931bc8f,
title = "Post-radiation gliomas",
abstract = "Aims and background: Radiotherapy is important in the treatment of neoplasm of the central nervous system, but various side efects, particularly neoplastic, have been described. Recently, post-radiation gliomas have been reported. Methods: The authors review 88 cases of cerebral glioma following radiotherapy in patients operated for neoplasms of the nervous system, including 6 personal cases of post-radiation gliomas treated in the Neurosurgical Division of the Department ot Neurological Sciences, 'La Sapienza' University, Rome. The criteria used to define this unusual pathologic association are discussed. Results: There was a male predominance. Post-radiation gliomas were particularly malignant, the average dose was 33 Gy, and average free latency was 9.6 years. The first disease was most frequently acute lymphatic leukemia. Conclusions: Post-radiation gliomas have particular features but do not present a histologic or clinical behavior different from analogous spontaneous gliomas. The fact that 88 cases have been reported in recent years suggests that a thorough biological, clinical study be carried out on this association.",
keywords = "astrocytoma, glioblastoma, radiation-induced tumor",
author = "M. Salvati and F. Puzzilli and R. Bristot and L. Cervoni",
year = "1994",
language = "English",
volume = "80",
pages = "220--223",
journal = "Tumori",
issn = "0300-8916",
publisher = "SAGE Publications Ltd",
number = "3",

}

TY - JOUR

T1 - Post-radiation gliomas

AU - Salvati, M.

AU - Puzzilli, F.

AU - Bristot, R.

AU - Cervoni, L.

PY - 1994

Y1 - 1994

N2 - Aims and background: Radiotherapy is important in the treatment of neoplasm of the central nervous system, but various side efects, particularly neoplastic, have been described. Recently, post-radiation gliomas have been reported. Methods: The authors review 88 cases of cerebral glioma following radiotherapy in patients operated for neoplasms of the nervous system, including 6 personal cases of post-radiation gliomas treated in the Neurosurgical Division of the Department ot Neurological Sciences, 'La Sapienza' University, Rome. The criteria used to define this unusual pathologic association are discussed. Results: There was a male predominance. Post-radiation gliomas were particularly malignant, the average dose was 33 Gy, and average free latency was 9.6 years. The first disease was most frequently acute lymphatic leukemia. Conclusions: Post-radiation gliomas have particular features but do not present a histologic or clinical behavior different from analogous spontaneous gliomas. The fact that 88 cases have been reported in recent years suggests that a thorough biological, clinical study be carried out on this association.

AB - Aims and background: Radiotherapy is important in the treatment of neoplasm of the central nervous system, but various side efects, particularly neoplastic, have been described. Recently, post-radiation gliomas have been reported. Methods: The authors review 88 cases of cerebral glioma following radiotherapy in patients operated for neoplasms of the nervous system, including 6 personal cases of post-radiation gliomas treated in the Neurosurgical Division of the Department ot Neurological Sciences, 'La Sapienza' University, Rome. The criteria used to define this unusual pathologic association are discussed. Results: There was a male predominance. Post-radiation gliomas were particularly malignant, the average dose was 33 Gy, and average free latency was 9.6 years. The first disease was most frequently acute lymphatic leukemia. Conclusions: Post-radiation gliomas have particular features but do not present a histologic or clinical behavior different from analogous spontaneous gliomas. The fact that 88 cases have been reported in recent years suggests that a thorough biological, clinical study be carried out on this association.

KW - astrocytoma

KW - glioblastoma

KW - radiation-induced tumor

UR - http://www.scopus.com/inward/record.url?scp=0027934264&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027934264&partnerID=8YFLogxK

M3 - Article

VL - 80

SP - 220

EP - 223

JO - Tumori

JF - Tumori

SN - 0300-8916

IS - 3

ER -