TY - JOUR
T1 - Post-tuberculosis (TB) treatment
T2 - The role of surgery and rehabilitation
AU - Visca, Dina
AU - Tiberi, Simon
AU - Centis, Rosella
AU - D'Ambrosio, Lia
AU - Pontali, Emanuele
AU - Mariani, Alessandro Wasum
AU - Zampogna, Elisabetta
AU - van den Boom, Martin
AU - Spanevello, Antonio
AU - Migliori, Giovanni Battista
N1 - Funding Information:
This research received no external funding. The article is part of the activities of the Global Tuberculosis Network (GTN; Committees on TB Treatment, Working Group on Pulmonary Rehabilitation and Global TB Consilium) and of the WHO Collaborating Centre for Tuberculosis and Lung Diseases, Tradate, ITA-80, 2017-2020-GBM/RC/LDA).
Publisher Copyright:
© 2020 by the authors.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/4/1
Y1 - 2020/4/1
N2 - Even though the majority of tuberculosis (TB) programmes consider their work completed when a patient is 'successfully' cured, patients often continue to suffer with post-treatment or surgical sequelae. This review focuses on describing the available evidence with regard to the diagnosis and management of post-treatment and surgical sequelae (pulmonary rehabilitation). We carried out a non-systematic literature review based on a PubMed search using specific key-words, including various combinations of 'TB', 'MDR-TB', 'XDR-TB', 'surgery', 'functional evaluation', 'sequelae' and 'pulmonary rehabilitation'. References of the most important papers were retrieved to improve the search accuracy. We identified the main areas of interest to describe the topic as follows: 1) 'Surgery', described through observational studies and reviews, systematic reviews and meta-analyses, IPD (individual data meta-analyses), and official guidelines (GRADE (Grading of Recommendations Assessment, Development and Evaluation) or not GRADE-based); 2) Post-TB treatment functional evaluation; and 3) Pulmonary rehabilitation interventions. We also highlighted the priority areas for research for the three main areas of interest. The collection of high-quality standardized variables would allow advances in the understanding of the need for, and effectiveness of, pulmonary rehabilitation at both the individual and the programmatic level. The initial evidence supports the importance of the adequate functional evaluation of these patients, which is necessary to identify those who will benefit from pulmonary rehabilitation.
AB - Even though the majority of tuberculosis (TB) programmes consider their work completed when a patient is 'successfully' cured, patients often continue to suffer with post-treatment or surgical sequelae. This review focuses on describing the available evidence with regard to the diagnosis and management of post-treatment and surgical sequelae (pulmonary rehabilitation). We carried out a non-systematic literature review based on a PubMed search using specific key-words, including various combinations of 'TB', 'MDR-TB', 'XDR-TB', 'surgery', 'functional evaluation', 'sequelae' and 'pulmonary rehabilitation'. References of the most important papers were retrieved to improve the search accuracy. We identified the main areas of interest to describe the topic as follows: 1) 'Surgery', described through observational studies and reviews, systematic reviews and meta-analyses, IPD (individual data meta-analyses), and official guidelines (GRADE (Grading of Recommendations Assessment, Development and Evaluation) or not GRADE-based); 2) Post-TB treatment functional evaluation; and 3) Pulmonary rehabilitation interventions. We also highlighted the priority areas for research for the three main areas of interest. The collection of high-quality standardized variables would allow advances in the understanding of the need for, and effectiveness of, pulmonary rehabilitation at both the individual and the programmatic level. The initial evidence supports the importance of the adequate functional evaluation of these patients, which is necessary to identify those who will benefit from pulmonary rehabilitation.
KW - Post-treatment sequelae
KW - Pulmonary rehabilitation
KW - Surgery
KW - TB
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U2 - 10.3390/APP10082734
DO - 10.3390/APP10082734
M3 - Review article
AN - SCOPUS:85084425249
VL - 10
JO - Applied Sciences (Switzerland)
JF - Applied Sciences (Switzerland)
SN - 2076-3417
IS - 8
M1 - 2734
ER -