Posterior corneal surface differences between non-laser in situ keratomileusis (LASIK) and 10-year post-LASIK myopic eyes

M.-L. Dai, Q.-M. Wang, Z.-S. Lin, Y. Yu, J.-H. Huang, G. Savini, J. Zhang, L. Wang, C.-C. Xu

Research output: Contribution to journalArticle

Abstract

Purpose: To evaluate the posterior corneal surface differences between non-laser in situ keratomileusis (LASIK) and 10-year post-LASIK myopic eyes. Methods: The study included 130 eyes from 65 patients, who were treated with myopic LASIK 10 years ago. In addition, 130 eyes from 65 unoperated myopic patients of matching present age and preoperative refraction were divided into control group. Data on the posterior corneal surface and anterior chamber were obtained from Pentacam software and compared between the groups. Postoperative visual acuity (VA) and refractive error were also analysed. Results: The mean preoperative spherical equivalent (SE) was −6.99 ± 1.78 dioptre (D) in the LASIK group. Ten years after surgery, the mean SE was −0.45 ± 1.22 D, the efficacy index was 0.98, and the safety index was 1.01. The posterior corneal elevations of the LASIK group at 2 mm corneal diameter were significantly lower than those of the control group. However, posterior corneal elevations at 6 mm corneal diameter were higher in the LASIK group than the controls (p 
Original languageEnglish
Pages (from-to)e127-e133
JournalActa Ophthalmologica
Volume96
Issue number2
DOIs
Publication statusPublished - 2018

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Lasers
Control Groups
Refractive Errors
Anterior Chamber
Visual Acuity
Software
Safety

Keywords

  • laser in situ keratomileusis
  • long-term
  • posterior corneal surface
  • safety
  • adult
  • anterior chamber depth
  • anterior chamber volume
  • Article
  • controlled study
  • corneal diameter
  • corrected distance visual acuity
  • cross-sectional study
  • female
  • human
  • keratomileusis
  • major clinical study
  • male
  • myopia
  • population research
  • postoperative period
  • preoperative period
  • priority journal
  • uncorrected distance visual acuity
  • visual acuity
  • visual system parameters
  • anterior eye chamber
  • comparative study
  • cornea endothelium
  • cornea stroma
  • excimer laser
  • eye refraction
  • follow up
  • middle aged
  • pathophysiology
  • physiology
  • procedures
  • therapeutic use
  • Adult
  • Anterior Chamber
  • Corneal Stroma
  • Cross-Sectional Studies
  • Endothelium, Corneal
  • Female
  • Follow-Up Studies
  • Humans
  • Keratomileusis, Laser In Situ
  • Lasers, Excimer
  • Male
  • Middle Aged
  • Myopia
  • Refraction, Ocular
  • Visual Acuity

Cite this

Posterior corneal surface differences between non-laser in situ keratomileusis (LASIK) and 10-year post-LASIK myopic eyes. / Dai, M.-L.; Wang, Q.-M.; Lin, Z.-S.; Yu, Y.; Huang, J.-H.; Savini, G.; Zhang, J.; Wang, L.; Xu, C.-C.

In: Acta Ophthalmologica, Vol. 96, No. 2, 2018, p. e127-e133.

Research output: Contribution to journalArticle

Dai, M.-L. ; Wang, Q.-M. ; Lin, Z.-S. ; Yu, Y. ; Huang, J.-H. ; Savini, G. ; Zhang, J. ; Wang, L. ; Xu, C.-C. / Posterior corneal surface differences between non-laser in situ keratomileusis (LASIK) and 10-year post-LASIK myopic eyes. In: Acta Ophthalmologica. 2018 ; Vol. 96, No. 2. pp. e127-e133.
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abstract = "Purpose: To evaluate the posterior corneal surface differences between non-laser in situ keratomileusis (LASIK) and 10-year post-LASIK myopic eyes. Methods: The study included 130 eyes from 65 patients, who were treated with myopic LASIK 10 years ago. In addition, 130 eyes from 65 unoperated myopic patients of matching present age and preoperative refraction were divided into control group. Data on the posterior corneal surface and anterior chamber were obtained from Pentacam software and compared between the groups. Postoperative visual acuity (VA) and refractive error were also analysed. Results: The mean preoperative spherical equivalent (SE) was −6.99 ± 1.78 dioptre (D) in the LASIK group. Ten years after surgery, the mean SE was −0.45 ± 1.22 D, the efficacy index was 0.98, and the safety index was 1.01. The posterior corneal elevations of the LASIK group at 2 mm corneal diameter were significantly lower than those of the control group. However, posterior corneal elevations at 6 mm corneal diameter were higher in the LASIK group than the controls (p ",
keywords = "laser in situ keratomileusis, long-term, posterior corneal surface, safety, adult, anterior chamber depth, anterior chamber volume, Article, controlled study, corneal diameter, corrected distance visual acuity, cross-sectional study, female, human, keratomileusis, major clinical study, male, myopia, population research, postoperative period, preoperative period, priority journal, uncorrected distance visual acuity, visual acuity, visual system parameters, anterior eye chamber, comparative study, cornea endothelium, cornea stroma, excimer laser, eye refraction, follow up, middle aged, pathophysiology, physiology, procedures, therapeutic use, Adult, Anterior Chamber, Corneal Stroma, Cross-Sectional Studies, Endothelium, Corneal, Female, Follow-Up Studies, Humans, Keratomileusis, Laser In Situ, Lasers, Excimer, Male, Middle Aged, Myopia, Refraction, Ocular, Visual Acuity",
author = "M.-L. Dai and Q.-M. Wang and Z.-S. Lin and Y. Yu and J.-H. Huang and G. Savini and J. Zhang and L. Wang and C.-C. Xu",
note = "Export Date: 25 January 2019 Correspondence Address: Xu, C.-C.; School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical UniversityChina; email: wzmcxcc@163.com Tradenames: Allegretto, Wavelight, Germany; M2, Moria, France Manufacturers: Wavelight, Germany; Moria, France References: Alio, J.L., Muftuoglu, O., Ortiz, D., Perez-Santonja, J.J., Artola, A., Ayala, M.J., Garcia, M.J., de Luna, G.C., Ten-year follow-up of laser in situ keratomileusis for myopia of up to -10 diopters (2008) Am J Ophthalmol, 145, pp. 46-54; Calossi, A., Corneal asphericity and spherical aberration (2007) J Refract Surg, 23, pp. 505-514; Chan, T.C., Liu, D., Yu, M., Jhanji, V., Longitudinal evaluation of posterior corneal elevation after laser refractive surgery using swept-source optical coherence tomography (2015) Ophthalmology, 122, pp. 687-692; Ciolino, J.B., Belin, M.W., Changes in the posterior cornea after laser in situ keratomileusis and photorefractive keratectomy (2006) J Cataract Refract Surg, 32, pp. 1426-1431; Ciolino, J.B., Khachikian, S.S., Cortese, M.J., Belin, M.W., Long-term stability of the posterior cornea after laser in situ keratomileusis (2007) J Cataract Refract Surg, 33, pp. 1366-1370; D'Arcy, F.M., Kirwan, C., O'Keefe, M., Ten year follow up of laser in situ keratomileusis for all levels of myopia (2012) Acta Ophthalmol, 90, pp. e335-e336; Du, X.L., Chen, M., Ma, L., Wang, X.X., Xie, L.X., [Comparison of Pentacam and OrbscanII systems for the diagnosis of keratoconus suspects] (2012) Zhonghua Yan Ke Za Zhi, 48, pp. 323-329; Dupps, W.J., Wilson, S.E., Biomechanics and wound healing in the cornea (2006) Exp Eye Res, 83, pp. 709-720; Goncalves, F.A., Goncalves, J.M., Corneal ectasia after LASIK in a patient with normal scheimpflug evaluation but a high Ectasia Risk Score (2013) J Refract Surg, 29, pp. 792-795; Gonzalez-Meijome, J.M., Villa-Collar, C., Montes-Mico, R., Gomes, A., Asphericity of the anterior human cornea with different corneal diameters (2007) J Cataract Refract Surg, 33, pp. 465-473; Grewal, D.S., Brar, G.S., Grewal, S.P., Posterior corneal elevation after LASIK with three flap techniques as measured by Pentacam (2011) J Refract Surg, 27, pp. 261-268; Ha, B.J., Kim, S.W., Kim, S.W., Kim, E.K., Kim, T.I., Pentacam and Orbscan II measurements of posterior corneal elevation before and after photorefractive keratectomy (2009) J Refract Surg, 25, pp. 290-295; Hou, J., Wang, Y., Li, J., Yang, X.Y., Zhang, L., [Changes of asphericity of posterior corneal surface after corneal refractive surgery] (2011) Zhonghua Yan Ke Za Zhi, 47, pp. 223-227; Kawamorita, T., Uozato, H., Kamiya, K., Bax, L., Tsutsui, K., Aizawa, D., Shimizu, K., Repeatability, reproducibility, and agreement characteristics of rotating Scheimpflug photography and scanning-slit corneal topography for corneal power measurement (2009) J Cataract Refract Surg, 35, pp. 127-133; Kim, H., Kim, H.J., Joo, C.K., Comparison of forward shift of posterior corneal surface after operation between LASIK and LASEK (2006) Ophthalmologica, 220, pp. 37-42; Lee, M.J., Lee, S.M., Lee, H.J., Wee, W.R., Lee, J.H., Kim, M.K., The changes of posterior corneal surface and high-order aberrations after refractive surgery in moderate myopia (2007) Korean J Ophthalmol, 21, pp. 131-136; Liu, Z., Li, Y., Cheng, Z., Zhou, F., Jiang, H., Li, J., Seven-year follow-up of LASIK for moderate to severe myopia (2008) J Refract Surg, 24, pp. 935-940; Martin, R., Rachidi, H., Stability of posterior corneal elevation one year after myopic laser in situ keratomileusis (2012) Clin Exp Optom, 95, pp. 177-186; Nishimura, R., Negishi, K., Saiki, M., Arai, H., Shimizu, S., Toda, I., Tsubota, K., No forward shifting of posterior corneal surface in eyes undergoing LASIK (2007) Ophthalmology, 114, pp. 1104-1110; Oliveira, C.M., Ribeiro, C., Franco, S., Corneal imaging with slit-scanning and Scheimpflug imaging techniques (2011) Clin Exp Optom, 94, pp. 33-42; Perez-Escudero, A., Dorronsoro, C., Sawides, L., Remon, L., Merayo-Lloves, J., Marcos, S., Minor influence of myopic laser in situ keratomileusis on the posterior corneal surface (2009) Invest Ophthalmol Vis Sci, 50, pp. 4146-4154; Read, S.A., Collins, M.J., Carney, L.G., Franklin, R.J., The topography of the central and peripheral cornea (2006) Invest Ophthalmol Vis Sci, 47, pp. 1404-1415; Roberts, C., The cornea is not a piece of plastic (2000) J Refract Surg, 16, pp. 407-413; Santhiago, M.R., Smadja, D., Gomes, B.F., Mello, G.R., Monteiro, M.L., Wilson, S.E., Randleman, J.B., Association between the percent tissue altered and post-laser in situ keratomileusis ectasia in eyes with normal preoperative topography (2014) Am J Ophthalmol, 158, pp. 87-95. , &, e81; Santhiago, M.R., Smajda, D., Wilson, S.E., Randleman, J.B., Relative contribution of flap thickness and ablation depth to the percentage of tissue altered in ectasia after laser in situ keratomileusis (2015) J Cataract Refract Surg, 41, pp. 2493-2500; Spadea, L., Cantera, E., Cortes, M., Conocchia, N.E., Stewart, C.W., Corneal ectasia after myopic laser in situ keratomileusis: a long-term study (2012) Clin Ophthalmol, 6, pp. 1801-1813; Sun, H.J., Park, J.W., Kim, S.W., Stability of the posterior corneal surface after laser surface ablation for myopia (2009) Cornea, 28, pp. 1019-1022; Sy, M.E., Ramirez-Miranda, A., Zarei-Ghanavati, S., Engle, J., Danesh, J., Hamilton, D.R., Comparison of posterior corneal imaging before and after LASIK using dual rotating scheimpflug and scanning slit-beam corneal tomography systems (2013) J Refract Surg, 29, pp. 96-101; Yan, P., Du, Z., Wu, N., Zhang, Y., Xu, Y., Minor influence of sub-bowman keratomileusis on the posterior corneal surface at early stage (2013) Curr Eye Res, 38, pp. 871-879",
year = "2018",
doi = "10.1111/aos.13532",
language = "English",
volume = "96",
pages = "e127--e133",
journal = "Acta Ophthalmologica",
issn = "1755-375X",
publisher = "Wiley-Blackwell Publishing Ltd",
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}

TY - JOUR

T1 - Posterior corneal surface differences between non-laser in situ keratomileusis (LASIK) and 10-year post-LASIK myopic eyes

AU - Dai, M.-L.

AU - Wang, Q.-M.

AU - Lin, Z.-S.

AU - Yu, Y.

AU - Huang, J.-H.

AU - Savini, G.

AU - Zhang, J.

AU - Wang, L.

AU - Xu, C.-C.

N1 - Export Date: 25 January 2019 Correspondence Address: Xu, C.-C.; School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical UniversityChina; email: wzmcxcc@163.com Tradenames: Allegretto, Wavelight, Germany; M2, Moria, France Manufacturers: Wavelight, Germany; Moria, France References: Alio, J.L., Muftuoglu, O., Ortiz, D., Perez-Santonja, J.J., Artola, A., Ayala, M.J., Garcia, M.J., de Luna, G.C., Ten-year follow-up of laser in situ keratomileusis for myopia of up to -10 diopters (2008) Am J Ophthalmol, 145, pp. 46-54; Calossi, A., Corneal asphericity and spherical aberration (2007) J Refract Surg, 23, pp. 505-514; Chan, T.C., Liu, D., Yu, M., Jhanji, V., Longitudinal evaluation of posterior corneal elevation after laser refractive surgery using swept-source optical coherence tomography (2015) Ophthalmology, 122, pp. 687-692; Ciolino, J.B., Belin, M.W., Changes in the posterior cornea after laser in situ keratomileusis and photorefractive keratectomy (2006) J Cataract Refract Surg, 32, pp. 1426-1431; Ciolino, J.B., Khachikian, S.S., Cortese, M.J., Belin, M.W., Long-term stability of the posterior cornea after laser in situ keratomileusis (2007) J Cataract Refract Surg, 33, pp. 1366-1370; D'Arcy, F.M., Kirwan, C., O'Keefe, M., Ten year follow up of laser in situ keratomileusis for all levels of myopia (2012) Acta Ophthalmol, 90, pp. e335-e336; Du, X.L., Chen, M., Ma, L., Wang, X.X., Xie, L.X., [Comparison of Pentacam and OrbscanII systems for the diagnosis of keratoconus suspects] (2012) Zhonghua Yan Ke Za Zhi, 48, pp. 323-329; Dupps, W.J., Wilson, S.E., Biomechanics and wound healing in the cornea (2006) Exp Eye Res, 83, pp. 709-720; Goncalves, F.A., Goncalves, J.M., Corneal ectasia after LASIK in a patient with normal scheimpflug evaluation but a high Ectasia Risk Score (2013) J Refract Surg, 29, pp. 792-795; Gonzalez-Meijome, J.M., Villa-Collar, C., Montes-Mico, R., Gomes, A., Asphericity of the anterior human cornea with different corneal diameters (2007) J Cataract Refract Surg, 33, pp. 465-473; Grewal, D.S., Brar, G.S., Grewal, S.P., Posterior corneal elevation after LASIK with three flap techniques as measured by Pentacam (2011) J Refract Surg, 27, pp. 261-268; Ha, B.J., Kim, S.W., Kim, S.W., Kim, E.K., Kim, T.I., Pentacam and Orbscan II measurements of posterior corneal elevation before and after photorefractive keratectomy (2009) J Refract Surg, 25, pp. 290-295; Hou, J., Wang, Y., Li, J., Yang, X.Y., Zhang, L., [Changes of asphericity of posterior corneal surface after corneal refractive surgery] (2011) Zhonghua Yan Ke Za Zhi, 47, pp. 223-227; Kawamorita, T., Uozato, H., Kamiya, K., Bax, L., Tsutsui, K., Aizawa, D., Shimizu, K., Repeatability, reproducibility, and agreement characteristics of rotating Scheimpflug photography and scanning-slit corneal topography for corneal power measurement (2009) J Cataract Refract Surg, 35, pp. 127-133; Kim, H., Kim, H.J., Joo, C.K., Comparison of forward shift of posterior corneal surface after operation between LASIK and LASEK (2006) Ophthalmologica, 220, pp. 37-42; Lee, M.J., Lee, S.M., Lee, H.J., Wee, W.R., Lee, J.H., Kim, M.K., The changes of posterior corneal surface and high-order aberrations after refractive surgery in moderate myopia (2007) Korean J Ophthalmol, 21, pp. 131-136; Liu, Z., Li, Y., Cheng, Z., Zhou, F., Jiang, H., Li, J., Seven-year follow-up of LASIK for moderate to severe myopia (2008) J Refract Surg, 24, pp. 935-940; Martin, R., Rachidi, H., Stability of posterior corneal elevation one year after myopic laser in situ keratomileusis (2012) Clin Exp Optom, 95, pp. 177-186; Nishimura, R., Negishi, K., Saiki, M., Arai, H., Shimizu, S., Toda, I., Tsubota, K., No forward shifting of posterior corneal surface in eyes undergoing LASIK (2007) Ophthalmology, 114, pp. 1104-1110; Oliveira, C.M., Ribeiro, C., Franco, S., Corneal imaging with slit-scanning and Scheimpflug imaging techniques (2011) Clin Exp Optom, 94, pp. 33-42; Perez-Escudero, A., Dorronsoro, C., Sawides, L., Remon, L., Merayo-Lloves, J., Marcos, S., Minor influence of myopic laser in situ keratomileusis on the posterior corneal surface (2009) Invest Ophthalmol Vis Sci, 50, pp. 4146-4154; Read, S.A., Collins, M.J., Carney, L.G., Franklin, R.J., The topography of the central and peripheral cornea (2006) Invest Ophthalmol Vis Sci, 47, pp. 1404-1415; Roberts, C., The cornea is not a piece of plastic (2000) J Refract Surg, 16, pp. 407-413; Santhiago, M.R., Smadja, D., Gomes, B.F., Mello, G.R., Monteiro, M.L., Wilson, S.E., Randleman, J.B., Association between the percent tissue altered and post-laser in situ keratomileusis ectasia in eyes with normal preoperative topography (2014) Am J Ophthalmol, 158, pp. 87-95. , &, e81; Santhiago, M.R., Smajda, D., Wilson, S.E., Randleman, J.B., Relative contribution of flap thickness and ablation depth to the percentage of tissue altered in ectasia after laser in situ keratomileusis (2015) J Cataract Refract Surg, 41, pp. 2493-2500; Spadea, L., Cantera, E., Cortes, M., Conocchia, N.E., Stewart, C.W., Corneal ectasia after myopic laser in situ keratomileusis: a long-term study (2012) Clin Ophthalmol, 6, pp. 1801-1813; Sun, H.J., Park, J.W., Kim, S.W., Stability of the posterior corneal surface after laser surface ablation for myopia (2009) Cornea, 28, pp. 1019-1022; Sy, M.E., Ramirez-Miranda, A., Zarei-Ghanavati, S., Engle, J., Danesh, J., Hamilton, D.R., Comparison of posterior corneal imaging before and after LASIK using dual rotating scheimpflug and scanning slit-beam corneal tomography systems (2013) J Refract Surg, 29, pp. 96-101; Yan, P., Du, Z., Wu, N., Zhang, Y., Xu, Y., Minor influence of sub-bowman keratomileusis on the posterior corneal surface at early stage (2013) Curr Eye Res, 38, pp. 871-879

PY - 2018

Y1 - 2018

N2 - Purpose: To evaluate the posterior corneal surface differences between non-laser in situ keratomileusis (LASIK) and 10-year post-LASIK myopic eyes. Methods: The study included 130 eyes from 65 patients, who were treated with myopic LASIK 10 years ago. In addition, 130 eyes from 65 unoperated myopic patients of matching present age and preoperative refraction were divided into control group. Data on the posterior corneal surface and anterior chamber were obtained from Pentacam software and compared between the groups. Postoperative visual acuity (VA) and refractive error were also analysed. Results: The mean preoperative spherical equivalent (SE) was −6.99 ± 1.78 dioptre (D) in the LASIK group. Ten years after surgery, the mean SE was −0.45 ± 1.22 D, the efficacy index was 0.98, and the safety index was 1.01. The posterior corneal elevations of the LASIK group at 2 mm corneal diameter were significantly lower than those of the control group. However, posterior corneal elevations at 6 mm corneal diameter were higher in the LASIK group than the controls (p 

AB - Purpose: To evaluate the posterior corneal surface differences between non-laser in situ keratomileusis (LASIK) and 10-year post-LASIK myopic eyes. Methods: The study included 130 eyes from 65 patients, who were treated with myopic LASIK 10 years ago. In addition, 130 eyes from 65 unoperated myopic patients of matching present age and preoperative refraction were divided into control group. Data on the posterior corneal surface and anterior chamber were obtained from Pentacam software and compared between the groups. Postoperative visual acuity (VA) and refractive error were also analysed. Results: The mean preoperative spherical equivalent (SE) was −6.99 ± 1.78 dioptre (D) in the LASIK group. Ten years after surgery, the mean SE was −0.45 ± 1.22 D, the efficacy index was 0.98, and the safety index was 1.01. The posterior corneal elevations of the LASIK group at 2 mm corneal diameter were significantly lower than those of the control group. However, posterior corneal elevations at 6 mm corneal diameter were higher in the LASIK group than the controls (p 

KW - laser in situ keratomileusis

KW - long-term

KW - posterior corneal surface

KW - safety

KW - adult

KW - anterior chamber depth

KW - anterior chamber volume

KW - Article

KW - controlled study

KW - corneal diameter

KW - corrected distance visual acuity

KW - cross-sectional study

KW - female

KW - human

KW - keratomileusis

KW - major clinical study

KW - male

KW - myopia

KW - population research

KW - postoperative period

KW - preoperative period

KW - priority journal

KW - uncorrected distance visual acuity

KW - visual acuity

KW - visual system parameters

KW - anterior eye chamber

KW - comparative study

KW - cornea endothelium

KW - cornea stroma

KW - excimer laser

KW - eye refraction

KW - follow up

KW - middle aged

KW - pathophysiology

KW - physiology

KW - procedures

KW - therapeutic use

KW - Adult

KW - Anterior Chamber

KW - Corneal Stroma

KW - Cross-Sectional Studies

KW - Endothelium, Corneal

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Keratomileusis, Laser In Situ

KW - Lasers, Excimer

KW - Male

KW - Middle Aged

KW - Myopia

KW - Refraction, Ocular

KW - Visual Acuity

U2 - 10.1111/aos.13532

DO - 10.1111/aos.13532

M3 - Article

VL - 96

SP - e127-e133

JO - Acta Ophthalmologica

JF - Acta Ophthalmologica

SN - 1755-375X

IS - 2

ER -