Posterior reversible encephalopathy syndrome associated with licorice consumption: A case report in a 10-year-old boy

Davide Tassinari, Rosalba Bergamaschi, Ilaria Corsini, Susanna Landini, Benedetta Romanin, Elisa Ballarini, Fabrizio De Ponti, Filomena Carfagnini, Francesco Toni, Filippo Bernardi

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background Posterior reversible encephalopathy syndrome is characterized by a combination of clinical-radiological findings and pathophysiologically by localized brain vasogenic edema. Many clinical illnesses may trigger the onset of posterior reversible encephalopathy syndrome and hypertension is present in about 80% of patients. Methods We describe a child with high consumption of licorice toffees who developed systemic hypertension followed by posterior reversible encephalopathy syndrome. Results This boy was hospitalized following a cluster of generalized tonic-clonic seizures. Monitoring his clinical parameters, we detected constant high blood pressure and a brain magnetic resonance scan showed a localized vasogenic edema; these symptoms suggested posterior reversible encephalopathy syndrome. He had been eating licorice toffees for a period of 4 months, consuming an estimated 72 mg of glycyrrhizic acid per day; this led to our assumption of the reason for his hypertension. Conclusion There are several reported examples of posterior reversible encephalopathy syndrome-induced licorice hypertension in adults, but none related to children. Our report examines a possible link between licorice consumption and hypertension/posterior reversible encephalopathy syndrome in children.

Original languageEnglish
Pages (from-to)457-459
Number of pages3
JournalPediatric Neurology
Volume52
Issue number4
DOIs
Publication statusPublished - Apr 1 2015

Fingerprint

Posterior Leukoencephalopathy Syndrome
Glycyrrhiza
Hypertension
Glycyrrhizic Acid
Brain Edema
Edema
Seizures
Magnetic Resonance Spectroscopy
Eating
Brain

Keywords

  • 11β-hydroxysteroid dehydrogenase
  • children
  • hypertension
  • licorice
  • PRES

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Neurology

Cite this

Tassinari, D., Bergamaschi, R., Corsini, I., Landini, S., Romanin, B., Ballarini, E., ... Bernardi, F. (2015). Posterior reversible encephalopathy syndrome associated with licorice consumption: A case report in a 10-year-old boy. Pediatric Neurology, 52(4), 457-459. https://doi.org/10.1016/j.pediatrneurol.2014.12.001

Posterior reversible encephalopathy syndrome associated with licorice consumption : A case report in a 10-year-old boy. / Tassinari, Davide; Bergamaschi, Rosalba; Corsini, Ilaria; Landini, Susanna; Romanin, Benedetta; Ballarini, Elisa; De Ponti, Fabrizio; Carfagnini, Filomena; Toni, Francesco; Bernardi, Filippo.

In: Pediatric Neurology, Vol. 52, No. 4, 01.04.2015, p. 457-459.

Research output: Contribution to journalArticle

Tassinari, D, Bergamaschi, R, Corsini, I, Landini, S, Romanin, B, Ballarini, E, De Ponti, F, Carfagnini, F, Toni, F & Bernardi, F 2015, 'Posterior reversible encephalopathy syndrome associated with licorice consumption: A case report in a 10-year-old boy', Pediatric Neurology, vol. 52, no. 4, pp. 457-459. https://doi.org/10.1016/j.pediatrneurol.2014.12.001
Tassinari, Davide ; Bergamaschi, Rosalba ; Corsini, Ilaria ; Landini, Susanna ; Romanin, Benedetta ; Ballarini, Elisa ; De Ponti, Fabrizio ; Carfagnini, Filomena ; Toni, Francesco ; Bernardi, Filippo. / Posterior reversible encephalopathy syndrome associated with licorice consumption : A case report in a 10-year-old boy. In: Pediatric Neurology. 2015 ; Vol. 52, No. 4. pp. 457-459.
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