Posterior reversible encephalopathy syndrome in intensive care medicine

Giuseppe Servillo, Francesca Bifulco, Edoardo De Robertis, Ornella Piazza, Pasquale Striano, Fabio Tortora, Salvatore Striano, Rosalba Tufano

Research output: Contribution to journalArticle

120 Citations (Scopus)

Abstract

Background: Posterior reversible encephalopathy syndrome (PRES) is a well-recognized clinico-neuroradiological transient condition. Early recognition is of paramount importance for prompt control of blood pressure or removal of precipitating factors and treatment of epileptic seizures or status epilepticus. Delay in the diagnosis and treatment may in fact results in death or in irreversible neurological sequelae. Discussion: PRES is characterized by headache, altered mental status, seizures, and visual disturbances and is associated with a number of different causes, most commonly acute hypertension, preeclampsia/eclampsia, and immunosuppressive agents. Clinical symptoms and neuroradiological findings are typically indistinguishable among the cases of PRES, regardless of underlying cause. Magnetic resonance studies typically show edema involving the white matter of cerebral posterior regions, especially parieto-occipital lobes but frontal and temporal lobes, and other encephalic structures may be involved. Conclusions: Intensivists and other physicians involved in the evaluation of patients with presumed PRES must be aware of the clinical spectrum of the associated conditions, the diagnostic modalities, and the correct treatment.

Original languageEnglish
Pages (from-to)230-236
Number of pages7
JournalIntensive Care Medicine
Volume33
Issue number2
DOIs
Publication statusPublished - Feb 2007

Fingerprint

Posterior Leukoencephalopathy Syndrome
Critical Care
Medicine
Precipitating Factors
Occipital Lobe
Eclampsia
Status Epilepticus
Frontal Lobe
Temporal Lobe
Immunosuppressive Agents
Pre-Eclampsia
Headache
Epilepsy
Edema
Seizures
Magnetic Resonance Spectroscopy
Therapeutics
Blood Pressure
Hypertension
Physicians

Keywords

  • Eclampsia
  • Encephalopathy
  • Intensive care
  • Magnetic resonance imaging
  • Posterior reversible encephalopathy syndrome

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

Cite this

Posterior reversible encephalopathy syndrome in intensive care medicine. / Servillo, Giuseppe; Bifulco, Francesca; De Robertis, Edoardo; Piazza, Ornella; Striano, Pasquale; Tortora, Fabio; Striano, Salvatore; Tufano, Rosalba.

In: Intensive Care Medicine, Vol. 33, No. 2, 02.2007, p. 230-236.

Research output: Contribution to journalArticle

Servillo, G, Bifulco, F, De Robertis, E, Piazza, O, Striano, P, Tortora, F, Striano, S & Tufano, R 2007, 'Posterior reversible encephalopathy syndrome in intensive care medicine', Intensive Care Medicine, vol. 33, no. 2, pp. 230-236. https://doi.org/10.1007/s00134-006-0459-0
Servillo, Giuseppe ; Bifulco, Francesca ; De Robertis, Edoardo ; Piazza, Ornella ; Striano, Pasquale ; Tortora, Fabio ; Striano, Salvatore ; Tufano, Rosalba. / Posterior reversible encephalopathy syndrome in intensive care medicine. In: Intensive Care Medicine. 2007 ; Vol. 33, No. 2. pp. 230-236.
@article{dc7b96a5651c46179328f0ae39a87a90,
title = "Posterior reversible encephalopathy syndrome in intensive care medicine",
abstract = "Background: Posterior reversible encephalopathy syndrome (PRES) is a well-recognized clinico-neuroradiological transient condition. Early recognition is of paramount importance for prompt control of blood pressure or removal of precipitating factors and treatment of epileptic seizures or status epilepticus. Delay in the diagnosis and treatment may in fact results in death or in irreversible neurological sequelae. Discussion: PRES is characterized by headache, altered mental status, seizures, and visual disturbances and is associated with a number of different causes, most commonly acute hypertension, preeclampsia/eclampsia, and immunosuppressive agents. Clinical symptoms and neuroradiological findings are typically indistinguishable among the cases of PRES, regardless of underlying cause. Magnetic resonance studies typically show edema involving the white matter of cerebral posterior regions, especially parieto-occipital lobes but frontal and temporal lobes, and other encephalic structures may be involved. Conclusions: Intensivists and other physicians involved in the evaluation of patients with presumed PRES must be aware of the clinical spectrum of the associated conditions, the diagnostic modalities, and the correct treatment.",
keywords = "Eclampsia, Encephalopathy, Intensive care, Magnetic resonance imaging, Posterior reversible encephalopathy syndrome",
author = "Giuseppe Servillo and Francesca Bifulco and {De Robertis}, Edoardo and Ornella Piazza and Pasquale Striano and Fabio Tortora and Salvatore Striano and Rosalba Tufano",
year = "2007",
month = "2",
doi = "10.1007/s00134-006-0459-0",
language = "English",
volume = "33",
pages = "230--236",
journal = "Intensive Care Medicine",
issn = "0342-4642",
publisher = "Springer Verlag",
number = "2",

}

TY - JOUR

T1 - Posterior reversible encephalopathy syndrome in intensive care medicine

AU - Servillo, Giuseppe

AU - Bifulco, Francesca

AU - De Robertis, Edoardo

AU - Piazza, Ornella

AU - Striano, Pasquale

AU - Tortora, Fabio

AU - Striano, Salvatore

AU - Tufano, Rosalba

PY - 2007/2

Y1 - 2007/2

N2 - Background: Posterior reversible encephalopathy syndrome (PRES) is a well-recognized clinico-neuroradiological transient condition. Early recognition is of paramount importance for prompt control of blood pressure or removal of precipitating factors and treatment of epileptic seizures or status epilepticus. Delay in the diagnosis and treatment may in fact results in death or in irreversible neurological sequelae. Discussion: PRES is characterized by headache, altered mental status, seizures, and visual disturbances and is associated with a number of different causes, most commonly acute hypertension, preeclampsia/eclampsia, and immunosuppressive agents. Clinical symptoms and neuroradiological findings are typically indistinguishable among the cases of PRES, regardless of underlying cause. Magnetic resonance studies typically show edema involving the white matter of cerebral posterior regions, especially parieto-occipital lobes but frontal and temporal lobes, and other encephalic structures may be involved. Conclusions: Intensivists and other physicians involved in the evaluation of patients with presumed PRES must be aware of the clinical spectrum of the associated conditions, the diagnostic modalities, and the correct treatment.

AB - Background: Posterior reversible encephalopathy syndrome (PRES) is a well-recognized clinico-neuroradiological transient condition. Early recognition is of paramount importance for prompt control of blood pressure or removal of precipitating factors and treatment of epileptic seizures or status epilepticus. Delay in the diagnosis and treatment may in fact results in death or in irreversible neurological sequelae. Discussion: PRES is characterized by headache, altered mental status, seizures, and visual disturbances and is associated with a number of different causes, most commonly acute hypertension, preeclampsia/eclampsia, and immunosuppressive agents. Clinical symptoms and neuroradiological findings are typically indistinguishable among the cases of PRES, regardless of underlying cause. Magnetic resonance studies typically show edema involving the white matter of cerebral posterior regions, especially parieto-occipital lobes but frontal and temporal lobes, and other encephalic structures may be involved. Conclusions: Intensivists and other physicians involved in the evaluation of patients with presumed PRES must be aware of the clinical spectrum of the associated conditions, the diagnostic modalities, and the correct treatment.

KW - Eclampsia

KW - Encephalopathy

KW - Intensive care

KW - Magnetic resonance imaging

KW - Posterior reversible encephalopathy syndrome

UR - http://www.scopus.com/inward/record.url?scp=33846888274&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846888274&partnerID=8YFLogxK

U2 - 10.1007/s00134-006-0459-0

DO - 10.1007/s00134-006-0459-0

M3 - Article

C2 - 17119920

AN - SCOPUS:33846888274

VL - 33

SP - 230

EP - 236

JO - Intensive Care Medicine

JF - Intensive Care Medicine

SN - 0342-4642

IS - 2

ER -