Postnatal catch-up fat after late preterm birth

Maria L. Giannì, Paola Roggero, Nadia Liotto, Orsola Amato, Pasqua Piemontese, Daniela Morniroli, Beatrice Bracco, Fabio Mosca

Research output: Contribution to journalArticlepeer-review


Background: Late preterm birth accounts for 70% of preterm births. The aim of the study was to investigate the postnatal weight gain and weight gain composition changes in a cohort of late preterm infants. Methods: A total of 49 late preterm infants (mean birth weight 2,496 ± 330 g and gestational age 35.2 ± 0.7 wks) underwent growth and body composition assessment by an air displacement plethysmography system on the fifth day of life, at term, and at 1 and 3 mo of corrected age. The reference group was composed of 40 healthy, full-term, breast-fed infants.Results:The late preterm infants showed a Δ fat mass gain between birth and term-corrected age equal to 182%. As compared with full-term infants, at term and 1 mo of corrected age mean weight (3,396 ± 390 vs. 3,074 ± 409 g and 4,521 ± 398 vs. 4,235 ± 673 g, respectively) and percentage of fat mass (16.1 ± 4.6 vs. 8.9 ± 2.9 and 22.6 ± 4.2 vs. 17.4 ± 4.0, respectively) were significantly higher in late preterm infants, whereas no difference among groups was found at 3 mo.Conclusion:Rapid postnatal catch-up fat was found in these infants. Further studies are needed to investigate whether this short-term increase in fat mass may modulate the risk of chronic diseases or represent an adaptive mechanism to extrauterine life.

Original languageEnglish
Pages (from-to)637-640
Number of pages4
JournalPediatric Research
Issue number6
Publication statusPublished - Dec 2012

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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