Abstract
Objective: To evaluate whether the low insulinlike growth factor I (IGF- I) levels that are observed in the neonate depend on the biological inactivity of the molecular forms of growth hormone (GH) or on the immaturity of the hepatic GH receptors during the early postnatal period. Materials and Methods: Serum samples were collected from 60 normal full-term neonates on day 5 and at 1 and 4 months of age to evaluate the GH concentrations by using both an immunofluorometric assay and Nb2 cell bioassay, as well as the GH- binding protein, IGF-1, and IGF-binding protein 3 values by radioimmunoassay. Results: Five-day-old neonates showed significantly higher (P
Original language | English |
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Pages (from-to) | 1068-1071 |
Number of pages | 4 |
Journal | Archives of Pediatrics and Adolescent Medicine |
Volume | 150 |
Issue number | 10 |
Publication status | Published - Oct 1996 |
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health