Analgesia postoperatoria: morfina per via peridurale vs buprenorfina per via sublinguale. Studio clinico comparativo.

E. M. Forastiere; V. Iacovacci; S. Proietti; F. Belcastro; L. Piastra; R. Greco

Analgesia postoperatoria: morfina per via peridurale vs buprenorfina per via sublinguale. Studio clinico comparativo.

Translated title of the contribution: Postoperative analgesia: peridural morphine versus sublingual buprenorphine. Comparative clinical study

E. M. Forastiere, V. Iacovacci, S. Proietti, F. Belcastro, L. Piastra, R. Greco

Istituto Regina Elena

Research output: Contribution to journal › Article › peer-review

Abstract

The authors herein present their personal series on the clinical evaluation of the analgesic efficacy of 2 opiodes, peridural morphine hydrochloride (0.5 mg/kg) administered to group A patients, and sublingual buprenorphine (0.4 mg) administered to group B patients in the management of post-operative pain in major abdominal surgery. The study was conducted on 44 patients, both male and female, classified as ASA II and III. Statistical analysis of cardiovascular parameters (BP and cardiac frequency), respiratory frequency and pain score showed an overlapping progression among the two groups. Spontaneous pain decreased significantly to zero at T6 (p <0.001). However, the necessity to administer buprenorphine more frequently after the sixth hour and the consequent increase in side effects, lead us to believe that the method used for group A patients is more advantageous.

Translated title of the contribution	Postoperative analgesia: peridural morphine versus sublingual buprenorphine. Comparative clinical study
Original language	Italian
Pages (from-to)	9-14
Number of pages	6
Journal	Minerva Anestesiologica
Volume	60
Issue number	10 Suppl 2
Publication status	Published - Oct 1994

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

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title = "Analgesia postoperatoria: morfina per via peridurale vs buprenorfina per via sublinguale. Studio clinico comparativo.",

abstract = "The authors herein present their personal series on the clinical evaluation of the analgesic efficacy of 2 opiodes, peridural morphine hydrochloride (0.5 mg/kg) administered to group A patients, and sublingual buprenorphine (0.4 mg) administered to group B patients in the management of post-operative pain in major abdominal surgery. The study was conducted on 44 patients, both male and female, classified as ASA II and III. Statistical analysis of cardiovascular parameters (BP and cardiac frequency), respiratory frequency and pain score showed an overlapping progression among the two groups. Spontaneous pain decreased significantly to zero at T6 (p <0.001). However, the necessity to administer buprenorphine more frequently after the sixth hour and the consequent increase in side effects, lead us to believe that the method used for group A patients is more advantageous.",

author = "Forastiere, {E. M.} and V. Iacovacci and S. Proietti and F. Belcastro and L. Piastra and R. Greco",

year = "1994",

month = oct,

language = "Italian",

volume = "60",

pages = "9--14",

journal = "Minerva Anestesiologica",

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publisher = "Edizioni Minerva Medica S.p.A.",

number = "10 Suppl 2",

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T2 - morfina per via peridurale vs buprenorfina per via sublinguale. Studio clinico comparativo.

AU - Forastiere, E. M.

AU - Iacovacci, V.

AU - Proietti, S.

AU - Belcastro, F.

AU - Piastra, L.

AU - Greco, R.

PY - 1994/10

Y1 - 1994/10

N2 - The authors herein present their personal series on the clinical evaluation of the analgesic efficacy of 2 opiodes, peridural morphine hydrochloride (0.5 mg/kg) administered to group A patients, and sublingual buprenorphine (0.4 mg) administered to group B patients in the management of post-operative pain in major abdominal surgery. The study was conducted on 44 patients, both male and female, classified as ASA II and III. Statistical analysis of cardiovascular parameters (BP and cardiac frequency), respiratory frequency and pain score showed an overlapping progression among the two groups. Spontaneous pain decreased significantly to zero at T6 (p <0.001). However, the necessity to administer buprenorphine more frequently after the sixth hour and the consequent increase in side effects, lead us to believe that the method used for group A patients is more advantageous.

AB - The authors herein present their personal series on the clinical evaluation of the analgesic efficacy of 2 opiodes, peridural morphine hydrochloride (0.5 mg/kg) administered to group A patients, and sublingual buprenorphine (0.4 mg) administered to group B patients in the management of post-operative pain in major abdominal surgery. The study was conducted on 44 patients, both male and female, classified as ASA II and III. Statistical analysis of cardiovascular parameters (BP and cardiac frequency), respiratory frequency and pain score showed an overlapping progression among the two groups. Spontaneous pain decreased significantly to zero at T6 (p <0.001). However, the necessity to administer buprenorphine more frequently after the sixth hour and the consequent increase in side effects, lead us to believe that the method used for group A patients is more advantageous.

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