Postoperative complications in gastrointestinal cancer patients: The joint role of the nutritional status and the nutritional support

Federico Bozzetti, Luca Gianotti, Mario Braga, Valerio Di Carlo, Luigi Mariani

Research output: Contribution to journalArticlepeer-review

Abstract

Background & aims: This study investigated the effects of nutritional support on postoperative complications, in relation with demographic and nutritional factors, intraoperative factors, type and routes of nutritional regimens. Methods: A series of 1410 subjects underwent major abdominal surgery for gastrointestinal cancer and received various types of nutritional support: standard intravenous fluids (SIF; n=149), total parenteral nutrition (TPN; n=368), enteral nutrition (EN; n=393), and immune-enhancing enteral nutrition (IEEN; n=500). Postoperative complications, considered as major (if lethal or requiring re-operation, or transfer to intensive care unit), or otherwise minor, were recorded. Results: Major and minor complications occurred in 101 (7.2%) and 446 (31.6%) patients, respectively. Factors correlated with postoperative complications at multivariate analysis were pancreatic surgery, (p

Original languageEnglish
Pages (from-to)698-709
Number of pages12
JournalClinical Nutrition
Volume26
Issue number6
DOIs
Publication statusPublished - Dec 2007

Keywords

  • Gastrointestinal cancer
  • Nutritional status
  • Nutritional support
  • Postoperative complications

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Endocrinology, Diabetes and Metabolism
  • Gastroenterology
  • Health Professions(all)
  • Medicine (miscellaneous)

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