Postradiation sarcoma of head and neck: Report of two cases

Alberto Bonetta, Maria Carolina Gelli, Giampaolo Zini, Cinzia Iotti, Verter Barbieri, Corrado Pedroni, Luciano Armaroli

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Aims and background: Post-irradiation sarcoma (PIS) is a rare, late side effect of radiotherapy and, consequently, its natural history is not well known. For this reason, two cases treated between 1975 and 1990 are described. Case reports: The authors describe one case of malignant fibrous histiocytoma grown in the larynx 111 months after conservative surgery and postoperative radiotherapy, and one case of soft tissue sarcoma developed in the oral cavity 72 months after radical interstitial low dose rate brachytherapy. Both patients had chronic distress of the soft tissues after the primary treatment. The patients are alive and well respectively at 94 and 18 months from salvage surgery. Discussion: The PIS of the head and neck region is a rare event, usually with a bad prognosis. An improvement in results could be possible with early diagnosis, followed by a timely excision, when anatomically possible. As the chronic suffering of the irradiated tissues may increase the risk of PIS, a longer and more frequent follow-up is advisable in these cases.

Original languageEnglish
Pages (from-to)270-272
Number of pages3
JournalTumori
Volume82
Issue number3
Publication statusPublished - May 1996

Fingerprint

Sarcoma
Neck
Head
Radiotherapy
Malignant Fibrous Histiocytoma
Brachytherapy
Larynx
Natural History
Psychological Stress
Mouth
Early Diagnosis
Therapeutics

Keywords

  • head and neck cancer
  • post-irradiation sarcoma
  • radiotherapy

ASJC Scopus subject areas

  • Cancer Research

Cite this

Bonetta, A., Gelli, M. C., Zini, G., Iotti, C., Barbieri, V., Pedroni, C., & Armaroli, L. (1996). Postradiation sarcoma of head and neck: Report of two cases. Tumori, 82(3), 270-272.

Postradiation sarcoma of head and neck : Report of two cases. / Bonetta, Alberto; Gelli, Maria Carolina; Zini, Giampaolo; Iotti, Cinzia; Barbieri, Verter; Pedroni, Corrado; Armaroli, Luciano.

In: Tumori, Vol. 82, No. 3, 05.1996, p. 270-272.

Research output: Contribution to journalArticle

Bonetta, A, Gelli, MC, Zini, G, Iotti, C, Barbieri, V, Pedroni, C & Armaroli, L 1996, 'Postradiation sarcoma of head and neck: Report of two cases', Tumori, vol. 82, no. 3, pp. 270-272.
Bonetta A, Gelli MC, Zini G, Iotti C, Barbieri V, Pedroni C et al. Postradiation sarcoma of head and neck: Report of two cases. Tumori. 1996 May;82(3):270-272.
Bonetta, Alberto ; Gelli, Maria Carolina ; Zini, Giampaolo ; Iotti, Cinzia ; Barbieri, Verter ; Pedroni, Corrado ; Armaroli, Luciano. / Postradiation sarcoma of head and neck : Report of two cases. In: Tumori. 1996 ; Vol. 82, No. 3. pp. 270-272.
@article{a454cf05246443d8b4a71848f57bd5fe,
title = "Postradiation sarcoma of head and neck: Report of two cases",
abstract = "Aims and background: Post-irradiation sarcoma (PIS) is a rare, late side effect of radiotherapy and, consequently, its natural history is not well known. For this reason, two cases treated between 1975 and 1990 are described. Case reports: The authors describe one case of malignant fibrous histiocytoma grown in the larynx 111 months after conservative surgery and postoperative radiotherapy, and one case of soft tissue sarcoma developed in the oral cavity 72 months after radical interstitial low dose rate brachytherapy. Both patients had chronic distress of the soft tissues after the primary treatment. The patients are alive and well respectively at 94 and 18 months from salvage surgery. Discussion: The PIS of the head and neck region is a rare event, usually with a bad prognosis. An improvement in results could be possible with early diagnosis, followed by a timely excision, when anatomically possible. As the chronic suffering of the irradiated tissues may increase the risk of PIS, a longer and more frequent follow-up is advisable in these cases.",
keywords = "head and neck cancer, post-irradiation sarcoma, radiotherapy",
author = "Alberto Bonetta and Gelli, {Maria Carolina} and Giampaolo Zini and Cinzia Iotti and Verter Barbieri and Corrado Pedroni and Luciano Armaroli",
year = "1996",
month = "5",
language = "English",
volume = "82",
pages = "270--272",
journal = "Tumori",
issn = "0300-8916",
publisher = "SAGE Publications Ltd",
number = "3",

}

TY - JOUR

T1 - Postradiation sarcoma of head and neck

T2 - Report of two cases

AU - Bonetta, Alberto

AU - Gelli, Maria Carolina

AU - Zini, Giampaolo

AU - Iotti, Cinzia

AU - Barbieri, Verter

AU - Pedroni, Corrado

AU - Armaroli, Luciano

PY - 1996/5

Y1 - 1996/5

N2 - Aims and background: Post-irradiation sarcoma (PIS) is a rare, late side effect of radiotherapy and, consequently, its natural history is not well known. For this reason, two cases treated between 1975 and 1990 are described. Case reports: The authors describe one case of malignant fibrous histiocytoma grown in the larynx 111 months after conservative surgery and postoperative radiotherapy, and one case of soft tissue sarcoma developed in the oral cavity 72 months after radical interstitial low dose rate brachytherapy. Both patients had chronic distress of the soft tissues after the primary treatment. The patients are alive and well respectively at 94 and 18 months from salvage surgery. Discussion: The PIS of the head and neck region is a rare event, usually with a bad prognosis. An improvement in results could be possible with early diagnosis, followed by a timely excision, when anatomically possible. As the chronic suffering of the irradiated tissues may increase the risk of PIS, a longer and more frequent follow-up is advisable in these cases.

AB - Aims and background: Post-irradiation sarcoma (PIS) is a rare, late side effect of radiotherapy and, consequently, its natural history is not well known. For this reason, two cases treated between 1975 and 1990 are described. Case reports: The authors describe one case of malignant fibrous histiocytoma grown in the larynx 111 months after conservative surgery and postoperative radiotherapy, and one case of soft tissue sarcoma developed in the oral cavity 72 months after radical interstitial low dose rate brachytherapy. Both patients had chronic distress of the soft tissues after the primary treatment. The patients are alive and well respectively at 94 and 18 months from salvage surgery. Discussion: The PIS of the head and neck region is a rare event, usually with a bad prognosis. An improvement in results could be possible with early diagnosis, followed by a timely excision, when anatomically possible. As the chronic suffering of the irradiated tissues may increase the risk of PIS, a longer and more frequent follow-up is advisable in these cases.

KW - head and neck cancer

KW - post-irradiation sarcoma

KW - radiotherapy

UR - http://www.scopus.com/inward/record.url?scp=0029949628&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029949628&partnerID=8YFLogxK

M3 - Article

C2 - 8693611

AN - SCOPUS:0029949628

VL - 82

SP - 270

EP - 272

JO - Tumori

JF - Tumori

SN - 0300-8916

IS - 3

ER -