Posture and gait in the early course of schizophrenia

Valentina Presta, Francesca Paraboschi, Filippo Marsella, Valeria Lucarini, Daniela Galli, Prisco Mirandola, Antonio Banchini, Carlo Marchesi, Laura Galuppo, Marco Vitale, Matteo Tonna, Giuliana Gobbi

Research output: Contribution to journalArticlepeer-review


While correlations between postural stability deficits and schizophrenia are well documented, information on dynamic motor alterations in schizophrenia are still scarce, and no data on their onset are available yet. Therefore, the aim of this study was i) to measure gait pattern(s) in patients with schizophrenia; ii) to identify posture and gait alterations which could potentially be used as a predictive clinical tool of the onset of the disorder. Body composition, posture and gait parameters were assessed in a group of 30 patients with schizophrenia and compared to 25 healthy subjects. Sway area was significantly higher in the schizophrenia group compared to controls regardless of whether the participants were in eyes open or eyes closed condition. Gait cadence and speed were significantly lower in patients with schizophrenia, while stride length was similar. We concluded that the combination of an increased sway area (independent from eye closure) and a gait cadence reduction —in the presence of normal gait speed and stride length—might be considered peculiar postural and gait profile characteristic of early schizophrenia.

Original languageEnglish
Article numbere0245661
JournalPLoS One
Issue number1 January
Publication statusPublished - Jan 2021

ASJC Scopus subject areas

  • General


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