PPARs signaling and cancer in the gastrointestinal system

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Nowadays, the study of the peroxisome proliferators activated receptors (PPARs) as potential targets for cancer prevention and therapy has gained a strong interest. From a biological point of view, the overall responsibility of PPARs in cancer development and progression is still controversial since several studies report both antiproliferative and tumor-promoting actions for these signaling molecules in human cancer cells and animal models. In this paper, we discuss PPARs functions in the context of different types of gastrointestinal cancer.

Original languageEnglish
Article number560846
JournalPPAR Research
DOIs
Publication statusPublished - 2012

Fingerprint

Peroxisome Proliferator-Activated Receptors
Gastrointestinal Neoplasms
Neoplasms
Animal Models
Therapeutics

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Drug Discovery

Cite this

PPARs signaling and cancer in the gastrointestinal system. / Pazienza, Valerio; Vinciguerra, Manlio; Mazzoccoli, Gianluigi.

In: PPAR Research, 2012.

Research output: Contribution to journalArticle

@article{6822a40ab4954ceb947e1045edeebaf1,
title = "PPARs signaling and cancer in the gastrointestinal system",
abstract = "Nowadays, the study of the peroxisome proliferators activated receptors (PPARs) as potential targets for cancer prevention and therapy has gained a strong interest. From a biological point of view, the overall responsibility of PPARs in cancer development and progression is still controversial since several studies report both antiproliferative and tumor-promoting actions for these signaling molecules in human cancer cells and animal models. In this paper, we discuss PPARs functions in the context of different types of gastrointestinal cancer.",
author = "Valerio Pazienza and Manlio Vinciguerra and Gianluigi Mazzoccoli",
year = "2012",
doi = "10.1155/2012/560846",
language = "English",
journal = "PPAR Research",
issn = "1687-4757",
publisher = "Hindawi Publishing Corporation",

}

TY - JOUR

T1 - PPARs signaling and cancer in the gastrointestinal system

AU - Pazienza, Valerio

AU - Vinciguerra, Manlio

AU - Mazzoccoli, Gianluigi

PY - 2012

Y1 - 2012

N2 - Nowadays, the study of the peroxisome proliferators activated receptors (PPARs) as potential targets for cancer prevention and therapy has gained a strong interest. From a biological point of view, the overall responsibility of PPARs in cancer development and progression is still controversial since several studies report both antiproliferative and tumor-promoting actions for these signaling molecules in human cancer cells and animal models. In this paper, we discuss PPARs functions in the context of different types of gastrointestinal cancer.

AB - Nowadays, the study of the peroxisome proliferators activated receptors (PPARs) as potential targets for cancer prevention and therapy has gained a strong interest. From a biological point of view, the overall responsibility of PPARs in cancer development and progression is still controversial since several studies report both antiproliferative and tumor-promoting actions for these signaling molecules in human cancer cells and animal models. In this paper, we discuss PPARs functions in the context of different types of gastrointestinal cancer.

UR - http://www.scopus.com/inward/record.url?scp=84867344609&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84867344609&partnerID=8YFLogxK

U2 - 10.1155/2012/560846

DO - 10.1155/2012/560846

M3 - Article

C2 - 23028383

AN - SCOPUS:84867344609

JO - PPAR Research

JF - PPAR Research

SN - 1687-4757

M1 - 560846

ER -