Practical tools to identify short children born small-for-gestational-age eligible for rhGH treatment according to Italian regulation

Gianluca Tornese; Flavia Pricci; Maria Chiara Pellegrin; Marika Villa; Daniela Rotondi; Elvira Agazio; Egidio Barbi

doi:10.1186/s13052-019-0715-x

Practical tools to identify short children born small-for-gestational-age eligible for rhGH treatment according to Italian regulation

Gianluca Tornese, Flavia Pricci, Maria Chiara Pellegrin, Marika Villa, Daniela Rotondi, Elvira Agazio, Egidio Barbi

Research output: Contribution to journal › Review article › peer-review

Abstract

Recombinant human growth hormone (rhGH) is an approved and effective treatment for short children born small for gestational age (SGA). Prevalence of children eligible for treatment as SGA is reported to be 1:1800. The latest data from the National Registry of Growth Hormone therapy (RNAOC) showed that the number of children treated with SGA indication is still small (prevalence 0.37/100,000) and these children are significantly less reported than those treated for growth hormone deficiency (GHD), although GHD prevalence is 1:4000-1:10,000. This means that many short children born SGA are still not properly identified, and therefore not treated with rhGH, or misdiagnosed as GHD. This article provides some practical tools for the identification of children eligible for rhGH treatment.

Original language	English
Article number	130
Journal	Italian Journal of Pediatrics
Volume	45
Issue number	1
DOIs	https://doi.org/10.1186/s13052-019-0715-x
Publication status	Published - Oct 21 2019

Keywords

Growth hormone
Italy
Small for gestational age

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

Access to Document

10.1186/s13052-019-0715-x

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Practical tools to identify short children born small-for-gestational-age eligible for rhGH treatment according to Italian regulation. / Tornese, Gianluca ; Pricci, Flavia; Pellegrin, Maria Chiara; Villa, Marika; Rotondi, Daniela; Agazio, Elvira ; Barbi, Egidio.

In: Italian Journal of Pediatrics, Vol. 45, No. 1, 130, 21.10.2019.

Research output: Contribution to journal › Review article › peer-review

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