Pre-ectopic vagal tone affects heart rate turbulence slope in heart failure

Giovanni D'Addio, Mario Cesarelli, Maria Romano, Giandomenico Pinna, Giuseppe Furgi, Nicola Ferrara, Franco Rengo

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Cardiovascular oscillations following spontaneous ventricular premature complexes (VPC) are described by the so-called heart rate turbulence (HRT) onset (TO) and slope (TS). Since HRT is a marker of baroreflex sensitivity, it can be hypothesized to be affected by the preceding VPC sympatovagal balance (pHF). The aim of this study is to investigate the relationship between HRT parameters and pHF in heart failure (HF) patients. We studied 75 24h ECG Holter recording of HF patients (62±9 years) performing a Spearman correlation analysis between TO, TS and pHF values. According to risk stratification standards, each post-VPC response was classified in 0-normal type or 1-abnormal category. Results showed a 53%, 27%,5%,6% of post-VPC respectively 0, 1a, 1b, 2-category, and a remaining 9% unclassified T0=0 values. pHF showed a moderate to good significant (p

Original languageEnglish
Title of host publicationComputing in Cardiology
Number of pages4
Publication statusPublished - 2012
Event39th Computing in Cardiology Conference, CinC 2012 - Krakow, Poland
Duration: Sep 9 2012Sep 12 2012


Other39th Computing in Cardiology Conference, CinC 2012

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Computer Science(all)


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