Praanalytik des prostata-spezifischen antigens

Translated title of the contribution: Preanalytical phase of prostate-specific antigen

Research output: Contribution to journalArticlepeer-review


The clinical use of prostate-specific antigen (PSA) is influenced by several preanalytical variables. Concerning iatrogenic influences, literature shows that after prostatic massage or transrectal ultrasonography there should be a delay of at least 24 hours before blood specimens are taken. In the case of digital rectal examination the correct minimum interval for blood drawing is two hours and in the case of needle biopsy 2 weeks. In > 40 years old men ejaculation is followed by a PSA increase for up to 2 days. Data on the effects of exercise on serum PSA are contradictory. Exercising on a bicycle ergometer induces an increase in PSA that depends on duration, intensity and on age. Stability of total PSA in serum on storage at low temperature (4°C, -20°C) is very good, while free PSA is less stable.

Translated title of the contributionPreanalytical phase of prostate-specific antigen
Original languageGerman
Pages (from-to)87-89
Number of pages3
Issue number2
Publication statusPublished - 1998


  • Biopsy, needle
  • Ejaculation
  • Massage
  • Physical examination
  • Prostate-specific antigen/serum
  • Prostatic neoplasms/ultrasonography
  • Specimen handling
  • Time factors

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Clinical Biochemistry


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