Precision of corneal thickness measurements obtained using the scheimpflug-placido imaging and agreement with ultrasound pachymetry

Jinhai Huang, Giacomo Savini, Chengfang Wang, Weicong Lu, Rongrong Gao, Yuanguang Li, Qinmei Wang, Yune Zhao

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose. To assess the reliability and comparability of measuring central corneal thickness (CCT) and thinnest corneal thickness (TCT) using a new Scheimpflug-Placido analyzer (TMS-5, Japan) and ultrasound (US) pachymetry. Methods. Seventy-six healthy subjects were prospectively measured 3 times by 1 operator using the TMS-5, 3 additional consecutive scans were performed by a second operator, and ultrasound (US) pachymetry measurements were taken. The test-retest repeatability (TRT), coefficient of variation (CoV), and intraclass correlation coefficient (ICC) were calculated to evaluate intraoperator repeatability and interoperator reproducibility. Agreement among the devices was assessed using Bland-Altman plots and 95% limits of agreement (LoA). Results. The intraoperators TRT and CoV were 0.90. The mean CCT and TCT measurements using the TMS-5 were 15.97 m (95% LoA from -26.42 to -5.52 m) and 20.32 m (95% LoA from -30.67 to -9.97 m) smaller, respectively, than those using US pachymetry. Conclusions. The TMS-5 shows good repeatability and reproducibility for measuring CCT and TCT in normal subjects but only moderate agreement with US pachymetry results. Caution is warranted before using these techniques interchangeably.

Original languageEnglish
Article number328798
JournalJournal of Ophthalmology
Volume2015
DOIs
Publication statusPublished - Feb 24 2015

ASJC Scopus subject areas

  • Ophthalmology

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