Abstract
Purpose: A preclinical investigation was undertaken to explore a treatment technique for total marrow irradiation using RapidArc, a volumetric modulated arc technique. Materials and Methods: Computed tomography datasets of 5 patients were included. Plans with eight overlapping coaxial arcs were optimized for 6-MV photon beams. Dose prescription was 12 Gy in 2 Gy per fraction, normalized so that 100% isodose covered 85% of the planning target volume (PTV). The PTV consisted of the whole skeleton (including ribs and sternum), from the top of the skull to the medium distal third of the femurs. Planning objectives for organs at risk (OARs) were constrained to a median dose
| Original language | English |
|---|---|
| Pages (from-to) | 628-636 |
| Number of pages | 9 |
| Journal | International Journal of Radiation Oncology Biology Physics |
| Volume | 80 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Jun 1 2011 |
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Keywords
- Intensity-modulated radiotherapy
- RapidArc
- Total-marrow irradiation
- Volumetric modulated arc therapy
ASJC Scopus subject areas
- Oncology
- Radiology Nuclear Medicine and imaging
- Radiation
- Cancer Research
Cite this
Preclinical assessment of volumetric modulated arc therapy for total marrow irradiation. / Fogliata, Antonella; Cozzi, Luca; Clivio, Alessandro; Ibatici, Adalberto; Mancosu, Pietro; Navarria, Piera; Nicolini, Giorgia; Santoro, Armando; Vanetti, Eugenio; Scorsetti, Marta.
In: International Journal of Radiation Oncology Biology Physics, Vol. 80, No. 2, 01.06.2011, p. 628-636.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Preclinical assessment of volumetric modulated arc therapy for total marrow irradiation
AU - Fogliata, Antonella
AU - Cozzi, Luca
AU - Clivio, Alessandro
AU - Ibatici, Adalberto
AU - Mancosu, Pietro
AU - Navarria, Piera
AU - Nicolini, Giorgia
AU - Santoro, Armando
AU - Vanetti, Eugenio
AU - Scorsetti, Marta
PY - 2011/6/1
Y1 - 2011/6/1
N2 - Purpose: A preclinical investigation was undertaken to explore a treatment technique for total marrow irradiation using RapidArc, a volumetric modulated arc technique. Materials and Methods: Computed tomography datasets of 5 patients were included. Plans with eight overlapping coaxial arcs were optimized for 6-MV photon beams. Dose prescription was 12 Gy in 2 Gy per fraction, normalized so that 100% isodose covered 85% of the planning target volume (PTV). The PTV consisted of the whole skeleton (including ribs and sternum), from the top of the skull to the medium distal third of the femurs. Planning objectives for organs at risk (OARs) were constrained to a median dose
AB - Purpose: A preclinical investigation was undertaken to explore a treatment technique for total marrow irradiation using RapidArc, a volumetric modulated arc technique. Materials and Methods: Computed tomography datasets of 5 patients were included. Plans with eight overlapping coaxial arcs were optimized for 6-MV photon beams. Dose prescription was 12 Gy in 2 Gy per fraction, normalized so that 100% isodose covered 85% of the planning target volume (PTV). The PTV consisted of the whole skeleton (including ribs and sternum), from the top of the skull to the medium distal third of the femurs. Planning objectives for organs at risk (OARs) were constrained to a median dose
KW - Intensity-modulated radiotherapy
KW - RapidArc
KW - Total-marrow irradiation
KW - Volumetric modulated arc therapy
UR - http://www.scopus.com/inward/record.url?scp=79955593890&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79955593890&partnerID=8YFLogxK
U2 - 10.1016/j.ijrobp.2010.11.028
DO - 10.1016/j.ijrobp.2010.11.028
M3 - Article
C2 - 21277109
AN - SCOPUS:79955593890
VL - 80
SP - 628
EP - 636
JO - International Journal of Radiation Oncology Biology Physics
JF - International Journal of Radiation Oncology Biology Physics
SN - 0360-3016
IS - 2
ER -