Preclinical assessment of volumetric modulated arc therapy for total marrow irradiation

Antonella Fogliata; Luca Cozzi; Alessandro Clivio; Adalberto Ibatici; Pietro Mancosu; Piera Navarria; Giorgia Nicolini; Armando Santoro; Eugenio Vanetti; Marta Scorsetti

doi:10.1016/j.ijrobp.2010.11.028

Preclinical assessment of volumetric modulated arc therapy for total marrow irradiation

Antonella Fogliata, Luca Cozzi, Alessandro Clivio, Adalberto Ibatici, Pietro Mancosu, Piera Navarria, Giorgia Nicolini, Armando Santoro, Eugenio Vanetti, Marta Scorsetti

Istituto Clinico Humanitas

Research output: Contribution to journal › Article › peer-review

Abstract

Purpose: A preclinical investigation was undertaken to explore a treatment technique for total marrow irradiation using RapidArc, a volumetric modulated arc technique. Materials and Methods: Computed tomography datasets of 5 patients were included. Plans with eight overlapping coaxial arcs were optimized for 6-MV photon beams. Dose prescription was 12 Gy in 2 Gy per fraction, normalized so that 100% isodose covered 85% of the planning target volume (PTV). The PTV consisted of the whole skeleton (including ribs and sternum), from the top of the skull to the medium distal third of the femurs. Planning objectives for organs at risk (OARs) were constrained to a median dose

Original language	English
Pages (from-to)	628-636
Number of pages	9
Journal	International Journal of Radiation Oncology Biology Physics
Volume	80
Issue number	2
DOIs	https://doi.org/10.1016/j.ijrobp.2010.11.028
Publication status	Published - Jun 1 2011

Keywords

Intensity-modulated radiotherapy
RapidArc
Total-marrow irradiation
Volumetric modulated arc therapy

ASJC Scopus subject areas

Oncology
Radiology Nuclear Medicine and imaging
Radiation
Cancer Research

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10.1016/j.ijrobp.2010.11.028

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Preclinical assessment of volumetric modulated arc therapy for total marrow irradiation. / Fogliata, Antonella; Cozzi, Luca; Clivio, Alessandro; Ibatici, Adalberto; Mancosu, Pietro ; Navarria, Piera; Nicolini, Giorgia; Santoro, Armando; Vanetti, Eugenio; Scorsetti, Marta.

In: International Journal of Radiation Oncology Biology Physics, Vol. 80, No. 2, 01.06.2011, p. 628-636.

Research output: Contribution to journal › Article › peer-review

Fogliata, Antonella ; Cozzi, Luca ; Clivio, Alessandro ; Ibatici, Adalberto ; Mancosu, Pietro ; Navarria, Piera ; Nicolini, Giorgia ; Santoro, Armando ; Vanetti, Eugenio ; Scorsetti, Marta. / Preclinical assessment of volumetric modulated arc therapy for total marrow irradiation. In: International Journal of Radiation Oncology Biology Physics. 2011 ; Vol. 80, No. 2. pp. 628-636.

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AU - Navarria, Piera

AU - Nicolini, Giorgia

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AU - Scorsetti, Marta

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Preclinical assessment of volumetric modulated arc therapy for total marrow irradiation

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Keywords

ASJC Scopus subject areas

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