Abstract
Background: In patients with unprovoked venous thromboembolism (VTE), the optimal duration of anticoagulation is anchored on estimating the risk of disease recurrence. Objectives: We aimed to develop a score that could predict the recurrence risk following a first episode of unprovoked VTE, pooling individual patient data from seven prospective studies. Methods: One thousand eight hundred and eighteen cases with unprovoked VTE treated for at least 3months with a vitamin K antagonist were available for analysis. Optimism-corrected Cox regression coefficients were used to develop a recurrence score that was subsequently internally validated by bootstrap analysis. Results: Abnormal D-dimer after stopping anticoagulation, age
Original language | English |
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Pages (from-to) | 1019-1025 |
Number of pages | 7 |
Journal | Journal of Thrombosis and Haemostasis |
Volume | 10 |
Issue number | 6 |
DOIs | |
Publication status | Published - Jun 2012 |
Keywords
- D-dimer
- Recurrence
- Risk
- Venous thrombosis
ASJC Scopus subject areas
- Hematology