Predicting disease recurrence in patients with previous unprovoked venous thromboembolism: A proposed prediction score (DASH)

A. Tosetto; A. Iorio; M. Marcucci; T. Baglin; M. Cushman; S. Eichinger; G. Palareti; D. Poli; R. C. Tait; J. Douketis

doi:10.1111/j.1538-7836.2012.04735.x

Predicting disease recurrence in patients with previous unprovoked venous thromboembolism: A proposed prediction score (DASH)

A. Tosetto, A. Iorio, M. Marcucci, T. Baglin, M. Cushman, S. Eichinger, G. Palareti, D. Poli, R. C. Tait, J. Douketis

Fondazione IRCCS Ca' Granda- Ospedale Maggiore Policlinico

Research output: Contribution to journal › Article › peer-review

Abstract

Background: In patients with unprovoked venous thromboembolism (VTE), the optimal duration of anticoagulation is anchored on estimating the risk of disease recurrence. Objectives: We aimed to develop a score that could predict the recurrence risk following a first episode of unprovoked VTE, pooling individual patient data from seven prospective studies. Methods: One thousand eight hundred and eighteen cases with unprovoked VTE treated for at least 3months with a vitamin K antagonist were available for analysis. Optimism-corrected Cox regression coefficients were used to develop a recurrence score that was subsequently internally validated by bootstrap analysis. Results: Abnormal D-dimer after stopping anticoagulation, age

Original language	English
Pages (from-to)	1019-1025
Number of pages	7
Journal	Journal of Thrombosis and Haemostasis
Volume	10
Issue number	6
DOIs	https://doi.org/10.1111/j.1538-7836.2012.04735.x
Publication status	Published - Jun 2012

Keywords

D-dimer
Recurrence
Risk
Venous thrombosis

ASJC Scopus subject areas

Hematology

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10.1111/j.1538-7836.2012.04735.x

Cite this

Tosetto, A., Iorio, A., Marcucci, M., Baglin, T., Cushman, M., Eichinger, S., Palareti, G., Poli, D., Tait, R. C., & Douketis, J. (2012). Predicting disease recurrence in patients with previous unprovoked venous thromboembolism: A proposed prediction score (DASH). Journal of Thrombosis and Haemostasis, 10(6), 1019-1025. https://doi.org/10.1111/j.1538-7836.2012.04735.x

Predicting disease recurrence in patients with previous unprovoked venous thromboembolism : A proposed prediction score (DASH). / Tosetto, A.; Iorio, A.; Marcucci, M.; Baglin, T.; Cushman, M.; Eichinger, S.; Palareti, G.; Poli, D.; Tait, R. C.; Douketis, J.

In: Journal of Thrombosis and Haemostasis, Vol. 10, No. 6, 06.2012, p. 1019-1025.

Research output: Contribution to journal › Article › peer-review

Tosetto, A, Iorio, A, Marcucci, M, Baglin, T, Cushman, M, Eichinger, S, Palareti, G, Poli, D, Tait, RC & Douketis, J 2012, 'Predicting disease recurrence in patients with previous unprovoked venous thromboembolism: A proposed prediction score (DASH)', Journal of Thrombosis and Haemostasis, vol. 10, no. 6, pp. 1019-1025. https://doi.org/10.1111/j.1538-7836.2012.04735.x

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abstract = "Background: In patients with unprovoked venous thromboembolism (VTE), the optimal duration of anticoagulation is anchored on estimating the risk of disease recurrence. Objectives: We aimed to develop a score that could predict the recurrence risk following a first episode of unprovoked VTE, pooling individual patient data from seven prospective studies. Methods: One thousand eight hundred and eighteen cases with unprovoked VTE treated for at least 3months with a vitamin K antagonist were available for analysis. Optimism-corrected Cox regression coefficients were used to develop a recurrence score that was subsequently internally validated by bootstrap analysis. Results: Abnormal D-dimer after stopping anticoagulation, age ",

keywords = "D-dimer, Recurrence, Risk, Venous thrombosis",

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AU - Tosetto, A.

AU - Iorio, A.

AU - Marcucci, M.

AU - Baglin, T.

AU - Cushman, M.

AU - Eichinger, S.

AU - Palareti, G.

AU - Poli, D.

AU - Tait, R. C.

AU - Douketis, J.

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Predicting disease recurrence in patients with previous unprovoked venous thromboembolism: A proposed prediction score (DASH)

Abstract

Keywords

ASJC Scopus subject areas

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