TY - JOUR
T1 - Predicting in-hospital mortality in acute type B aortic dissection
T2 - evidence from International Registry of Acute Aortic Dissection.
AU - Tolenaar, Jip L.
AU - Froehlich, Whit
AU - Jonker, Frederik H W
AU - Upchurch, Gilbert R.
AU - Rampoldi, Vincenzo
AU - Tsai, Thomas T.
AU - Bossone, Eduardo
AU - Evangelista, Arturo
AU - O'Gara, Patrick
AU - Pape, Linda
AU - Montgomery, Dan
AU - Isselbacher, Eric M.
AU - Nienaber, Christoph A.
AU - Eagle, Kim A.
AU - Trimarchi, Santi
PY - 2014
Y1 - 2014
N2 - The outcome of patients with acute type B aortic dissection (ABAD) is strongly related to their clinical presentation. The purpose of this study was to investigate predictors for mortality among patients presenting with ABAD and to create a predictive model to estimate individual risk of in-hospital mortality using the International Registry of Acute Aortic Dissection (IRAD). All patients with ABAD enrolled in IRAD between 1996 and 2013 were included for analysis. Multivariable logistic regression analysis was used to investigate predictors of in-hospital mortality. Significant risk factors for in-hospital death were used to develop a prediction model. A total of 1034 patients with ABAD were included for analysis (673 men; mean age, 63.5±14.0 years), with an overall in-hospital mortality of 10.6%. In multivariable analysis, the following variables at admission were independently associated with increased in-hospital mortality: increasing age (odds ratio [OR], 1.03; 95% confidence interval [CI], 1.00-1.06; P=0.044), hypotension/shock (OR, 6.43; 95% CI, 2.88-18.98; P=0.001), periaortic hematoma (OR, 3.06; 95% CI, 1.38-6.78; P=0.006), descending diameter ≥5.5 cm (OR, 6.04; 95% CI, 2.87-12.73; P
AB - The outcome of patients with acute type B aortic dissection (ABAD) is strongly related to their clinical presentation. The purpose of this study was to investigate predictors for mortality among patients presenting with ABAD and to create a predictive model to estimate individual risk of in-hospital mortality using the International Registry of Acute Aortic Dissection (IRAD). All patients with ABAD enrolled in IRAD between 1996 and 2013 were included for analysis. Multivariable logistic regression analysis was used to investigate predictors of in-hospital mortality. Significant risk factors for in-hospital death were used to develop a prediction model. A total of 1034 patients with ABAD were included for analysis (673 men; mean age, 63.5±14.0 years), with an overall in-hospital mortality of 10.6%. In multivariable analysis, the following variables at admission were independently associated with increased in-hospital mortality: increasing age (odds ratio [OR], 1.03; 95% confidence interval [CI], 1.00-1.06; P=0.044), hypotension/shock (OR, 6.43; 95% CI, 2.88-18.98; P=0.001), periaortic hematoma (OR, 3.06; 95% CI, 1.38-6.78; P=0.006), descending diameter ≥5.5 cm (OR, 6.04; 95% CI, 2.87-12.73; P
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U2 - 10.1161/CIRCULATIONAHA.113.007117
DO - 10.1161/CIRCULATIONAHA.113.007117
M3 - Article
C2 - 25200055
AN - SCOPUS:84908140617
VL - 130
JO - Circulation
JF - Circulation
SN - 0009-7322
IS - 11 Suppl 1
ER -