Predicting in-hospital mortality in acute type B aortic dissection: evidence from International Registry of Acute Aortic Dissection.

Jip L. Tolenaar, Whit Froehlich, Frederik H W Jonker, Gilbert R. Upchurch, Vincenzo Rampoldi, Thomas T. Tsai, Eduardo Bossone, Arturo Evangelista, Patrick O'Gara, Linda Pape, Dan Montgomery, Eric M. Isselbacher, Christoph A. Nienaber, Kim A. Eagle, Santi Trimarchi

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Abstract

The outcome of patients with acute type B aortic dissection (ABAD) is strongly related to their clinical presentation. The purpose of this study was to investigate predictors for mortality among patients presenting with ABAD and to create a predictive model to estimate individual risk of in-hospital mortality using the International Registry of Acute Aortic Dissection (IRAD). All patients with ABAD enrolled in IRAD between 1996 and 2013 were included for analysis. Multivariable logistic regression analysis was used to investigate predictors of in-hospital mortality. Significant risk factors for in-hospital death were used to develop a prediction model. A total of 1034 patients with ABAD were included for analysis (673 men; mean age, 63.5±14.0 years), with an overall in-hospital mortality of 10.6%. In multivariable analysis, the following variables at admission were independently associated with increased in-hospital mortality: increasing age (odds ratio [OR], 1.03; 95% confidence interval [CI], 1.00-1.06; P=0.044), hypotension/shock (OR, 6.43; 95% CI, 2.88-18.98; P=0.001), periaortic hematoma (OR, 3.06; 95% CI, 1.38-6.78; P=0.006), descending diameter ≥5.5 cm (OR, 6.04; 95% CI, 2.87-12.73; P

Original languageEnglish
JournalCirculation
Volume130
Issue number11 Suppl 1
DOIs
Publication statusPublished - 2014

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ASJC Scopus subject areas

  • Physiology (medical)
  • Cardiology and Cardiovascular Medicine

Cite this

Tolenaar, J. L., Froehlich, W., Jonker, F. H. W., Upchurch, G. R., Rampoldi, V., Tsai, T. T., Bossone, E., Evangelista, A., O'Gara, P., Pape, L., Montgomery, D., Isselbacher, E. M., Nienaber, C. A., Eagle, K. A., & Trimarchi, S. (2014). Predicting in-hospital mortality in acute type B aortic dissection: evidence from International Registry of Acute Aortic Dissection. Circulation, 130(11 Suppl 1). https://doi.org/10.1161/CIRCULATIONAHA.113.007117