Abstract
The rate of Parkinson's Disease (PD) progression in the initial post-diagnosis years can vary significantly. In this work, a methodology for the extraction of the most informative features for predicting rapid progression of the disease is proposed, using public data from the Parkinson's Progression Markers Initiative (PPMI) and machine learning techniques. The aim is to determine if a patient is at risk of expressing rapid progression of PD symptoms from the baseline evaluation and as close to diagnosis as possible. By examining the records of 409 patients from the PPMI dataset, the features with the best predictive value at baseline patient evaluation are found to be sleep problems, daytime sleepiness and fatigue, motor symptoms at legs, cognition impairment, early axial and facial symptoms and in the most rapidly advanced cases speech issues, loss of smell and affected leg muscle reflexes.
Original language | English |
---|---|
Title of host publication | 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society |
Subtitle of host publication | Smarter Technology for a Healthier World, EMBC 2017 - Proceedings |
Publisher | Institute of Electrical and Electronics Engineers Inc. |
Pages | 3898-3901 |
Number of pages | 4 |
ISBN (Electronic) | 9781509028092 |
DOIs | |
Publication status | Published - Sep 13 2017 |
Event | 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017 - Jeju Island, Korea, Republic of Duration: Jul 11 2017 → Jul 15 2017 |
Conference
Conference | 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017 |
---|---|
Country | Korea, Republic of |
City | Jeju Island |
Period | 7/11/17 → 7/15/17 |
ASJC Scopus subject areas
- Signal Processing
- Biomedical Engineering
- Computer Vision and Pattern Recognition
- Health Informatics