Aim. The aim of this study was to determine if low-dose dobutamine stress echocardiography (LD-DSE) is associated with functional capacity in unselected elderly patients with chronic heart failure. Methods. This was a prospective trial. Thirty five consecutive patients were included, with age ≥65 years and left ventricular dysfunction (12 ischemic), by blindly assessed LD-DSE and cardiopulmonary exercise testing (CPT). Contractile reserve was defined as a change (Δ) in wall motion score index (WMSI) ≤0.2 at peak dose dobutamine. At CPT treadmill exercise time, peak VO2, %Vo 2, and VE/VCO2 slope were determined. Preserved functional capacity was defined as percent of maximal predicted O2 consumption (%VO2) ≥80%. Baseline NT-proBNP plasma levels were assessed. Results. CPT variables were not related to clinical and baseline echocardiography characteristics but were related to WMSI (exercise time, P=0.004; peak VO2 P = 0.008; %VO2, P2, P2, respectively). Conclusion. Contractile reserve elicited at LD-DSE is associated with functional capacity in unselected elderly patients with chronic heart failure.
|Number of pages||9|
|Publication status||Published - Jun 2008|
- Echocardiography, stress
- Functional residual capacity
- Heart failure
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine