Predictive and prognostic significance of neuron-specific enolase (NSE) in non-small cell lung cancer

Marcello Tiseo, Andrea Ardizzoni, Mara Argenide Cafferata, Maura Loprevite, Maurizio Chiaramondia, Rosangela Filiberti, Paola Marroni, Francesco Grossi, Michela Paganuzzi

Research output: Contribution to journalArticlepeer-review

Abstract

Background: The predictive and prognostic role of neuron-specific enolase (NSE) in non-small cell lung cancer (NSCLC) is still under debate. Patients and Methods: To study these aspects, serum NSE was prospectively measured at baseline of first-line chemotherapy treatment and tested for correlation with clinical outcome in 129 advanced NSCLC patients. Results: An objective response was achieved in 27 out of 65 (41.5%) patients with NSE

Original languageEnglish
Pages (from-to)507-513
Number of pages7
JournalAnticancer Research
Volume28
Issue number1 B
Publication statusPublished - Jan 2008

Keywords

  • Neuron-specific enolase
  • Non-small cell lung cancer
  • NSE
  • Predictive factor
  • Prognostic factor

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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