Predictive value of coagulation tests in arterial thrombosis

Marco Cattaneo, Pier Mannuccio Mannucci

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

In five large-scale prospective studies the predictive value of hemostatic parameters indicating the occurrence of arterial thrombotic diseases has been estimated in healthy individuals. All the studies have consistently found a statistically significant association between hyperfibrinogenemia and arterial thrombotic diseases. In two studies, increased levels of factor VII were associated with an increased incidence of ischemic heart disease. The relationship between arterial occlusive diseases and plasma levels of fibrinogen or factor VII was closer than that for other well established risk factors such as plasma cholesterol. These data indicate the important pathogenetic role carried out by alterations of the clotting system in occlusive arterial diseases.

Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalLa Ricerca in Clinica e in Laboratorio
Volume18
Issue number1
DOIs
Publication statusPublished - Jan 1988

Fingerprint

Predictive Value of Tests
Arterial Occlusive Diseases
Factor VII
Coagulation
Thrombosis
Hemostatics
Fibrinogen
Myocardial Ischemia
Cholesterol
Prospective Studies
Incidence
Plasmas

Keywords

  • Factor VII
  • Fibrinogen
  • Myocardial infarction
  • Predictive tests
  • Stroke

ASJC Scopus subject areas

  • Clinical Biochemistry

Cite this

Predictive value of coagulation tests in arterial thrombosis. / Cattaneo, Marco; Mannucci, Pier Mannuccio.

In: La Ricerca in Clinica e in Laboratorio, Vol. 18, No. 1, 01.1988, p. 1-7.

Research output: Contribution to journalArticle

@article{0b0b2aa322884e3b83676c2628e76e7f,
title = "Predictive value of coagulation tests in arterial thrombosis",
abstract = "In five large-scale prospective studies the predictive value of hemostatic parameters indicating the occurrence of arterial thrombotic diseases has been estimated in healthy individuals. All the studies have consistently found a statistically significant association between hyperfibrinogenemia and arterial thrombotic diseases. In two studies, increased levels of factor VII were associated with an increased incidence of ischemic heart disease. The relationship between arterial occlusive diseases and plasma levels of fibrinogen or factor VII was closer than that for other well established risk factors such as plasma cholesterol. These data indicate the important pathogenetic role carried out by alterations of the clotting system in occlusive arterial diseases.",
keywords = "Factor VII, Fibrinogen, Myocardial infarction, Predictive tests, Stroke",
author = "Marco Cattaneo and Mannucci, {Pier Mannuccio}",
year = "1988",
month = "1",
doi = "10.1007/BF02918813",
language = "English",
volume = "18",
pages = "1--7",
journal = "Ricerca in Clinica e in Laboratorio",
issn = "0940-5437",
publisher = "Springer Verlag",
number = "1",

}

TY - JOUR

T1 - Predictive value of coagulation tests in arterial thrombosis

AU - Cattaneo, Marco

AU - Mannucci, Pier Mannuccio

PY - 1988/1

Y1 - 1988/1

N2 - In five large-scale prospective studies the predictive value of hemostatic parameters indicating the occurrence of arterial thrombotic diseases has been estimated in healthy individuals. All the studies have consistently found a statistically significant association between hyperfibrinogenemia and arterial thrombotic diseases. In two studies, increased levels of factor VII were associated with an increased incidence of ischemic heart disease. The relationship between arterial occlusive diseases and plasma levels of fibrinogen or factor VII was closer than that for other well established risk factors such as plasma cholesterol. These data indicate the important pathogenetic role carried out by alterations of the clotting system in occlusive arterial diseases.

AB - In five large-scale prospective studies the predictive value of hemostatic parameters indicating the occurrence of arterial thrombotic diseases has been estimated in healthy individuals. All the studies have consistently found a statistically significant association between hyperfibrinogenemia and arterial thrombotic diseases. In two studies, increased levels of factor VII were associated with an increased incidence of ischemic heart disease. The relationship between arterial occlusive diseases and plasma levels of fibrinogen or factor VII was closer than that for other well established risk factors such as plasma cholesterol. These data indicate the important pathogenetic role carried out by alterations of the clotting system in occlusive arterial diseases.

KW - Factor VII

KW - Fibrinogen

KW - Myocardial infarction

KW - Predictive tests

KW - Stroke

UR - http://www.scopus.com/inward/record.url?scp=0023674550&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023674550&partnerID=8YFLogxK

U2 - 10.1007/BF02918813

DO - 10.1007/BF02918813

M3 - Article

C2 - 3375737

AN - SCOPUS:0023674550

VL - 18

SP - 1

EP - 7

JO - Ricerca in Clinica e in Laboratorio

JF - Ricerca in Clinica e in Laboratorio

SN - 0940-5437

IS - 1

ER -