Predictive value of Obsessive-Compulsive Personality Disorder in antiobsessional pharmacological treatment

Paolo Cavedini, Stefano Erzegovesi, Paolo Ronchi, Laura Bellodi

Research output: Contribution to journalArticle


Previous reports have stressed the implication of Personality Disorders as predictors of a poorer treatment outcome in Obsessive Compulsive Disorder (OCD). The aim of this study was to see whether or not Obsessive-Compulsive Personality Disorder in Obsessive-Compulsive Disorder may be predictive for a poorer outcome to antiobsessive pro-serotonergic pharmacological treatment. For this purpose, 30 OCD patients were divided into two groups according to the presence or absence of Obsessive-Compulsive Personality Disorder. Ten-week standardized treatments with oral SRI drugs were given to look for different outcomes between the two groups in Obsessive-Compulsive symptom severity. At the end of the study we found that the presence of Obsessive-Compulsive Personality Disorder, along with the total number of Personality Disorders, did predict poorer response to pharmacological treatment in OCD.

Original languageEnglish
Pages (from-to)45-49
Number of pages5
JournalEuropean Neuropsychopharmacology
Issue number1
Publication statusPublished - Feb 1 1997


  • clomipramine
  • fluvoxamine
  • Obsessive-Compulsive Disorder
  • personality disorders

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Biological Psychiatry
  • Neurology
  • Pharmacology
  • Psychology(all)

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