Predictors and statistical models in congenital diaphragmatic hernia

Germana Casaccia, Lucilla Ravà, Pietro Bagolan, Vincenzo Maria Di Ciommo

Research output: Contribution to journalArticle

Abstract

Despite advances in intensive care, congenital diaphragmatic hernia (CDH) maintains a risk of death >35%. Mortality predictors have been claimed, using logistic regression. When the outcome of interest is rare (i.e. 2 ≥ 90 mmHg as protective factors. Using logistic regression, liver herniation and birth weight did not maintain the significance. The exposition risks for pnx, female gender and gestational age were overestimated. The odds ratio measured by logistic regression overestimated the exposition risks. Since the mortality rate is confirmed to be >20% and the exposition risks, measured by logistic regression, are misleading, the log-binomial model should be consider in CDH binary outcome studies. According to the mortality predictors identified, making every effort to plan delivery at term and lowering the risk of pnx could improve the outcome.

Original languageEnglish
Pages (from-to)411-414
Number of pages4
JournalPediatric Surgery International
Volume24
Issue number4
DOIs
Publication statusPublished - Apr 2008

Keywords

  • Congenital diaphragmatic hernia
  • Predictors of mortality
  • Prognosis
  • Statistical analysis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery

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