Predictors of human papilloma virus (HPV) infection in Italian women

M. C. Cercato, L. Mariani, A. Vocaturo, A. Carrone, I. Terrenato, G. Morano, M. Benevolo, F. Rollo, C. Germelli, F. Paolini, A. Venuti

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

HPV infection is a "necessary cause" of cervical cancer and it is sexually transmitted. Due to upcoming mass vaccination investigation on risk factors for infection is the basis to implement prophylactic strategy even in older women. The aim of the study was to evaluate predictors of high-risk (HR) HPV infection in adult women. Between 2006 and 2008, 100 women aged >18 years, with no previous treatment for cervical lesions, were screened for HR HPV infection in Rome, Italy. Risk factors for HPV infection were investigated through a questionnaire including: ethnicity, religion, education, marital status, sexual behavior, gynecological and obstetrical history, smoking and alcohol intake. Multivariate analysis identified the "never married-separated/divorced" status (OR: 3.38; 95% CI: 1.14-10.12) as predictor of HPV infection, while having a higher age at the first sexual intercourse (FSI) shows a protective effect (OR: 0.84; 95% CI: 0.71-1.00). A trend for the association between the infection and having more than three lifetime partners was also observed (OR: 2.57; 95% CI: 0.86-7.71). No significant association was found for other demographic characteristics investigated. These findings provide a contribution in the knowledge of an adult population defining a "high-risk" sexual behavioral profile and could be helpful to target prophylactic strategies in older woman. J. Med. Virol. 82:1921-1927, 2010.

Original languageEnglish
Pages (from-to)1921-1927
Number of pages7
JournalJournal of Medical Virology
Volume82
Issue number11
DOIs
Publication statusPublished - Nov 2010

Fingerprint

Papillomaviridae
Virus Diseases
Coitus
Mass Vaccination
Divorce
Marital Status
Religion
Infection
Uterine Cervical Neoplasms
Sexual Behavior
Italy
Multivariate Analysis
Smoking
History
Alcohols
Demography
Education

Keywords

  • Cervical cancer
  • Epidemiology
  • HPV
  • Questionnaire
  • Risk factors
  • Sexual behavior

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases

Cite this

Predictors of human papilloma virus (HPV) infection in Italian women. / Cercato, M. C.; Mariani, L.; Vocaturo, A.; Carrone, A.; Terrenato, I.; Morano, G.; Benevolo, M.; Rollo, F.; Germelli, C.; Paolini, F.; Venuti, A.

In: Journal of Medical Virology, Vol. 82, No. 11, 11.2010, p. 1921-1927.

Research output: Contribution to journalArticle

Cercato, MC, Mariani, L, Vocaturo, A, Carrone, A, Terrenato, I, Morano, G, Benevolo, M, Rollo, F, Germelli, C, Paolini, F & Venuti, A 2010, 'Predictors of human papilloma virus (HPV) infection in Italian women', Journal of Medical Virology, vol. 82, no. 11, pp. 1921-1927. https://doi.org/10.1002/jmv.21887
Cercato, M. C. ; Mariani, L. ; Vocaturo, A. ; Carrone, A. ; Terrenato, I. ; Morano, G. ; Benevolo, M. ; Rollo, F. ; Germelli, C. ; Paolini, F. ; Venuti, A. / Predictors of human papilloma virus (HPV) infection in Italian women. In: Journal of Medical Virology. 2010 ; Vol. 82, No. 11. pp. 1921-1927.
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