Predictors of postoperative morbidity after laparoscopic versus open radical hysterectomy plus external beam radiotherapy: A propensity-matched comparison

Giorgio Bogani, Antonella Cromi, Maurizio Serati, Edoardo Di Naro, Stefano Uccella, Nicoletta Donadello, Fabio Ghezzi

Research output: Contribution to journalArticlepeer-review

Abstract

Background Identification of peri-operative variables predicting postoperative morbidity may improve postoperative patients' care. We aimed to identify patients' characteristics and operative factors predictive of early (≤30-day) and late (≤6-month) morbidity in cervical cancer patients undergoing surgery plus external beam radiotherapy (EBRT). Methods We studied 45 propensity-matched patient pairs (90 patients) undergoing laparoscopic radical hysterectomy (LRH) plus EBRT vs. abdominal radical hysterectomy (RAH) plus EBRT. Basic descriptive, multivariable and artificial neuronal network analyses (ANN) were used to design predicting models influencing outcomes. Results Baseline characteristics of the study populations were similar. Patients undergoing LRH experienced lower blood loss (200 (range, 10-700) vs. 400 (range, 100-2000) ml; P

Original languageEnglish
Pages (from-to)893-898
Number of pages6
JournalJournal of Surgical Oncology
Volume110
Issue number7
DOIs
Publication statusPublished - Dec 1 2014

Keywords

  • cervical cancer
  • late complications
  • morbidity
  • radical hysterectomy
  • radiotherapy

ASJC Scopus subject areas

  • Surgery
  • Oncology
  • Medicine(all)

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