Predictors of postoperative morbidity after laparoscopic versus open radical hysterectomy plus external beam radiotherapy: A propensity-matched comparison

Giorgio Bogani; Antonella Cromi; Maurizio Serati; Edoardo Di Naro; Stefano Uccella; Nicoletta Donadello; Fabio Ghezzi

doi:10.1002/jso.23747

Predictors of postoperative morbidity after laparoscopic versus open radical hysterectomy plus external beam radiotherapy: A propensity-matched comparison

Giorgio Bogani, Antonella Cromi, Maurizio Serati, Edoardo Di Naro, Stefano Uccella, Nicoletta Donadello, Fabio Ghezzi

Fondazione IRCCS Istituto Nazionale dei Tumori

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Abstract

Background Identification of peri-operative variables predicting postoperative morbidity may improve postoperative patients' care. We aimed to identify patients' characteristics and operative factors predictive of early (≤30-day) and late (≤6-month) morbidity in cervical cancer patients undergoing surgery plus external beam radiotherapy (EBRT). Methods We studied 45 propensity-matched patient pairs (90 patients) undergoing laparoscopic radical hysterectomy (LRH) plus EBRT vs. abdominal radical hysterectomy (RAH) plus EBRT. Basic descriptive, multivariable and artificial neuronal network analyses (ANN) were used to design predicting models influencing outcomes. Results Baseline characteristics of the study populations were similar. Patients undergoing LRH experienced lower blood loss (200 (range, 10-700) vs. 400 (range, 100-2000) ml; P

Original language	English
Pages (from-to)	893-898
Number of pages	6
Journal	Journal of Surgical Oncology
Volume	110
Issue number	7
DOIs	https://doi.org/10.1002/jso.23747
Publication status	Published - Dec 1 2014

Keywords

cervical cancer
late complications
morbidity
radical hysterectomy
radiotherapy

ASJC Scopus subject areas

Surgery
Oncology
Medicine(all)

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10.1002/jso.23747

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Predictors of postoperative morbidity after laparoscopic versus open radical hysterectomy plus external beam radiotherapy : A propensity-matched comparison. / Bogani, Giorgio; Cromi, Antonella; Serati, Maurizio; Di Naro, Edoardo; Uccella, Stefano; Donadello, Nicoletta; Ghezzi, Fabio.

In: Journal of Surgical Oncology, Vol. 110, No. 7, 01.12.2014, p. 893-898.

Research output: Contribution to journal › Article › peer-review

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AU - Di Naro, Edoardo

AU - Uccella, Stefano

AU - Donadello, Nicoletta

AU - Ghezzi, Fabio

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Predictors of postoperative morbidity after laparoscopic versus open radical hysterectomy plus external beam radiotherapy: A propensity-matched comparison

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Keywords

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