TY - JOUR
T1 - Predictors of response to anti-TNF therapy in RA patients with moderate or high DAS28scores
AU - Atzeni, Fabiola
AU - Bongiovanni, Sara
AU - Marchesoni, Antonio
AU - Filippini, Matteo
AU - Caporali, Roberto
AU - Gorla, Roberto
AU - Cavagna, Lorenzo
AU - Favalli, Ennio Giulio
AU - Saccardo, Francesco
AU - Sarzi-Puttini, Piercarlo
PY - 2014/1
Y1 - 2014/1
N2 - Objectives: To identify the clinical factors predicting a good clinical response to anti-TNF therapy in rheumatoid arthritis (RA) patients entered in the LORHEN registry after 5. years of treatment with anti-TNF agents and divided into two groups on the basis of their baseline DAS28scores (moderate. >. 3.2-5.1 [MDA] and high. >. 5.1 [HDA]). Methods: Disease activity at baseline and after 12. months was assessed using the DAS28, and response was evaluated using the EULAR improvement criteria. Results: The study involved 1300patients with established RA: 975 with HDA and 325with MDA. After a mean 36-month, 29.6% of the patients had a DAS28 score of less or equal to 2.6 (HDA 25.8% vs. MDA 43.0%; P
AB - Objectives: To identify the clinical factors predicting a good clinical response to anti-TNF therapy in rheumatoid arthritis (RA) patients entered in the LORHEN registry after 5. years of treatment with anti-TNF agents and divided into two groups on the basis of their baseline DAS28scores (moderate. >. 3.2-5.1 [MDA] and high. >. 5.1 [HDA]). Methods: Disease activity at baseline and after 12. months was assessed using the DAS28, and response was evaluated using the EULAR improvement criteria. Results: The study involved 1300patients with established RA: 975 with HDA and 325with MDA. After a mean 36-month, 29.6% of the patients had a DAS28 score of less or equal to 2.6 (HDA 25.8% vs. MDA 43.0%; P
KW - Anti-TNF
KW - DAS28 scores
KW - High and moderate disease activity
KW - Predictive factors
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U2 - 10.1016/j.jbspin.2013.04.005
DO - 10.1016/j.jbspin.2013.04.005
M3 - Article
C2 - 23731638
AN - SCOPUS:84893808326
VL - 81
SP - 37
EP - 40
JO - Revue du Rhumatisme (English Edition)
JF - Revue du Rhumatisme (English Edition)
SN - 0035-2659
IS - 1
ER -